13 Result(s)

Article

Erratum: Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype

Correction to: Neuropsychopharmacology (2016) 41, 2647–2657; doi:10.1038/npp.2016.60; published online 18 May 2016 Page 9: The following should be added to the Acknowledgments section: ‘We gratefully acknowled...

Hisham Ziauddeen, Liam J Nestor, Naresh Subramaniam, Chris Dodds… in Neuropsychopharmacology (2018)

Article

Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype

The A118G single-nucleotide polymorphism (SNP rs1799971) in the μ-opioid receptor gene, OPRM1, has been much studied in relation to alcohol use disorders. The reported effects of allelic variation at this SNP on ...

Hisham Ziauddeen, Liam J Nestor, Naresh Subramaniam, Chris Dodds… in Neuropsychopharmacology (2016)

Article

Oxytocin Modulation of Amygdala Functional Connectivity to Fearful Faces in Generalized Social Anxiety Disorder

The neuropeptide oxytocin (OXT) is thought to attenuate anxiety by dampening amygdala reactivity to threat in individuals with generalized social anxiety disorder (GSAD). Because the brain is organized into ne...

Stephanie M Gorka, Daniel A Fitzgerald, Izelle Labuschagne… in Neuropsychopharmacology (2015)

Article

Modulation of Resting-State Amygdala-Frontal Functional Connectivity by Oxytocin in Generalized Social Anxiety Disorder

Generalized social anxiety disorder (GSAD) is characterized by aberrant patterns of amygdala-frontal connectivity to social signals of threat and at rest. The neuropeptide oxytocin (OXT) modulates anxiety, str...

Sonam Dodhia, Avinash Hosanagar, Daniel A Fitzgerald… in Neuropsychopharmacology (2014)

Article

Inhibition of Opioid Transmission at the μ-Opioid Receptor Prevents Both Food Seeking and Binge-Like Eating

Endogenous opioids, and in particular μ-opioid receptors, have been linked to hedonic and rewarding mechanisms engaged during palatable food intake. The aim of this study was to investigate the effects of GSK1...

Chiara Giuliano, Trevor W Robbins, Pradeep J Nathan… in Neuropsychopharmacology (2012)

Article

Oxytocin Attenuates Amygdala Reactivity to Fear in Generalized Social Anxiety Disorder

Patients with generalized social anxiety disorder (GSAD) exhibit heightened activation of the amygdala in response to social cues conveying threat (eg, fearful/angry faces). The neuropeptide oxytocin (OXT) dec...

Izelle Labuschagne, K Luan Phan, Amanda Wood, Mike Angstadt… in Neuropsychopharmacology (2010)

Article

Differential Effects of Acute Serotonin and Dopamine Depletion on Prepulse Inhibition and P50 Suppression Measures of Sensorimotor and Sensory Gating in Humans

Schizophrenia is associated with impairments of sensorimotor and sensory gating as measured by prepulse inhibition (PPI) of the acoustic startle response and P50 suppression of the auditory event-related poten...

Collette Mann, Rodney J Croft, Kirsty E Scholes, Alan Dunne… in Neuropsychopharmacology (2008)

Article

Acute Serotonin and Dopamine Depletion Improves Attentional Control: Findings from the Stroop Task

Schizophrenia is associated with impairments of attentional control on classic experimental paradigms such as the Stroop task. However, at a basic level the neurochemical mechanisms that may be responsible for...

Kirsty E Scholes, Ben J Harrison, Barry V O'Neill, Sumie Leung… in Neuropsychopharmacology (2007)

Article

Estrogen Prevents 5-HT_1A Receptor-Induced Disruptions of Prepulse Inhibition in Healthy Women

The sex steroid hormone, estrogen, has been proposed to be protective against schizophrenia. This study examined the effects of estrogen treatment on modulation of prepulse inhibition (PPI) by the serotonin-1A...

Andrea Gogos, Pradeep J Nathan, Valérie Guille, Rodney J Croft… in Neuropsychopharmacology (2006)

Article

Is the Loudness Dependence of the Auditory Evoked Potential a Sensitive and Selective In Vivo Marker of Central Serotonergic Function?

Pradeep J Nathan, Barry O'Neill, Rodney J Croft in Neuropsychopharmacology (2005)

Article

L-Tryptophan Challenge and Cognitive Deficits in Bipolar Disorder: Evidence for Hyperserotonergic and Hypodopaminergic Mechanisms

Pradeep J Nathan, Ben J Harrison in Neuropsychopharmacology (2003)

Article

Antidepressants and Emotional Processing

Pradeep J Nathan, Andrew H Kemp, Ben J Harrison in Neuropsychopharmacology (2003)