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Article
Emotion Regulatory Brain Function and SSRI Treatment in PTSD: Neural Correlates and Predictors of Change
Posttraumatic stress disorder (PTSD)—a chronic, debilitating condition, broadly characterized by emotion dysregulation—is prevalent among US military personnel who have returned from Operations Enduring Freedo...
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Article
Oxytocin Modulation of Amygdala Functional Connectivity to Fearful Faces in Generalized Social Anxiety Disorder
The neuropeptide oxytocin (OXT) is thought to attenuate anxiety by dampening amygdala reactivity to threat in individuals with generalized social anxiety disorder (GSAD). Because the brain is organized into ne...
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Article
Open AccessResting state amygdala-prefrontal connectivity predicts symptom change after cognitive behavioral therapy in generalized social anxiety disorder
Aberrant amygdala-prefrontal interactions at rest and during emotion processing are implicated in the pathophysiology of generalized social anxiety disorder (gSAD), a common disorder characterized by fears of ...
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Article
Open AccessAberrant amygdala functional connectivity at rest in pediatric anxiety disorders
Childhood onset of anxiety disorders is associated with greater functional impairment and burden across the lifespan. Recent work suggests that generalized anxiety disorder (GAD) is characterized by dysfunctio...
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Article
Effects of oxycodone on brain responses to emotional images
Evidence from animal and human studies suggests that opiate drugs decrease emotional responses to negative stimuli and increase responses to positive stimuli. Such emotional effects may motivate misuse of oxyc...
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Article
Modulation of Resting-State Amygdala-Frontal Functional Connectivity by Oxytocin in Generalized Social Anxiety Disorder
Generalized social anxiety disorder (GSAD) is characterized by aberrant patterns of amygdala-frontal connectivity to social signals of threat and at rest. The neuropeptide oxytocin (OXT) modulates anxiety, str...
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Article
Crack cocaine use impairs anterior cingulate and prefrontal cortex function in women with HIV infection
Crack cocaine use is associated with impaired verbal memory in HIV-infected women more than uninfected women. To understand the neural basis for this impairment, this study examined the effects of crack cocain...
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Article
Alcohol attenuates amygdala–frontal connectivity during processing social signals in heavy social drinkers
Convergent evidence shows that alcohol exerts its effects on social behavior via modulation of amygdala reactivity to affective stimuli. Given that affective processing involves dynamic interactions between th...
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Article
Open AccessAnterior cingulate cortex and insula response during indirect and direct processing of emotional faces in generalized social anxiety disorder
Generalized social anxiety disorder (gSAD) is associated with a heightened neural sensitivity to signals that convey threat, as evidenced by exaggerated amygdala and/or insula activation when processing face s...
