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  1. Article

    Open Access

    Trends in inpatient care for psychiatric disorders in NHS hospitals across England, 1998/99–2019/20: an observational time series analysis

    It is unclear how hospitals are responding to the mental health needs of the population in England, against a backdrop of diminishing resources. We aimed to document patterns in hospital activity by psychiatri...

    Michelle Degli Esposti, Hisham Ziauddeen in Social Psychiatry and Psychiatric Epidemio… (2022)

  2. Article

    Open Access

    Characterizing cerebral metabolite profiles in anorexia and bulimia nervosa and their associations with habitual behavior

    Anorexia nervosa (AN) and bulimia nervosa (BN) are associated with altered brain structure and function, as well as increased habitual behavior. This neurobehavioral profile may implicate neurochemical changes...

    Margaret L. Westwater, Alexander G. Murley in Translational Psychiatry (2022)

  3. Article

    Open Access

    BMI-related cortical morphometry changes are associated with altered white matter structure

    While gross measures of brain structure have shown alterations with increasing body mass index (BMI), the extent and nature of such changes has varied substantially across studies. Here, we sought to determine...

    Nenad Medic, Peter Kochunov, Hisham Ziauddeen in International Journal of Obesity (2019)

  4. Article

    Erratum: Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype

    Correction to: Neuropsychopharmacology (2016) 41, 2647–2657; doi:10.1038/npp.2016.60; published online 18 May 2016 Page 9: The following should be added to the Acknowledgments section: ‘We gratefully acknowled...

    Hisham Ziauddeen, Liam J Nestor, Naresh Subramaniam, Chris Dodds in Neuropsychopharmacology (2018)

  5. Article

    Open Access

    Oxytocin administration suppresses hypothalamic activation in response to visual food cues

    The aim of this study was to use functional neuroimaging to investigate whether oxytocin modulates the neural response to visual food cues in brain regions involved in the control of food intake. Twenty-four n...

    Agatha A. van der Klaauw, Hisham Ziauddeen, Julia M. Keogh in Scientific Reports (2017)

  6. Article

    Open Access

    Sugar addiction: the state of the science

    As obesity rates continue to climb, the notion that overconsumption reflects an underlying ‘food addiction’ (FA) has become increasingly influential. An increasingly popular theory is that sugar acts as an add...

    Margaret L. Westwater, Paul C. Fletcher, Hisham Ziauddeen in European Journal of Nutrition (2016)

  7. Article

    Open Access

    Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype

    The A118G single-nucleotide polymorphism (SNP rs1799971) in the μ-opioid receptor gene, OPRM1, has been much studied in relation to alcohol use disorders. The reported effects of allelic variation at this SNP on ...

    Hisham Ziauddeen, Liam J Nestor, Naresh Subramaniam, Chris Dodds in Neuropsychopharmacology (2016)

  8. Article

    Open Access

    Abnormal Frontostriatal Activity During Unexpected Reward Receipt in Depression and Schizophrenia: Relationship to Anhedonia

    Alterations in reward processes may underlie motivational and anhedonic symptoms in depression and schizophrenia. However it remains unclear whether these alterations are disorder-specific or shared, and wheth...

    Nuria Segarra, Antonio Metastasio, Hisham Ziauddeen in Neuropsychopharmacology (2016)

  9. Article

    Food addiction: is there a baby in the bathwater?

    Hisham Ziauddeen, I. Sadaf Farooqi, Paul C. Fletcher in Nature Reviews Neuroscience (2012)

  10. No Access

    Article

    Obesity and the brain: how convincing is the addiction model?

    A growing field of research aims to examine the potential overlap between the characteristics and underlying mechanisms of drug addiction and obesity. Here, Fletcher and colleagues argue that there is not yet ...

    Hisham Ziauddeen, I. Sadaf Farooqi, Paul C. Fletcher in Nature Reviews Neuroscience (2012)