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Article
Upregulation of eIF2α by m6A modification accelerates the proliferation of pulmonary artery smooth muscle cells in MCT-induced pulmonary arterial hypertension rats
Pulmonary arterial hypertension (PAH) is a malignant cardiovascular disease. Eukaryotic initiation factor 2α (eIF2α) plays an important role in the proliferation of pulmonary artery smooth muscle cells (PASMCs...
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Article
Zinc and Inflammatory Bowel Disease: From Clinical Study to Animal Experiment
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract (GI) with a high incidence rate globally, and IBD patients are often accompanied by zinc deficiency. This review...
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Article
Prelacrimal recess approach for maxillary sinus inverted papilloma: a 15-year experience from a single center
This large retrospective, single-center, follow-up study investigated the endoscopic prelacrimal recess approach (PLRA) for treating maxillary sinus inverted papilloma (MSIP).
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Article
Open AccessCorrelation between ovarian follicular development and Hippo pathway in polycystic ovary syndrome
For women of childbearing age, the biggest problem caused by polycystic ovary syndrome (PCOS) is infertility, which is mainly caused by anovulation, abnormal follicular development, proliferation of small antr...
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Article
Open AccessSkeletal muscle-secreted DLPC orchestrates systemic energy homeostasis by enhancing adipose browning
MyoD is a skeletal muscle-specifically expressed transcription factor and plays a critical role in regulating myogenesis during muscle development and regeneration. However, whether myofibers-expressed MyoD ex...
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Article
Targeting Vascular Smooth Muscle Cell Senescence: A Novel Strategy for Vascular Diseases
Vascular diseases are a major threat to human health, characterized by high rates of morbidity, mortality, and disability. VSMC senescence contributes to dramatic changes in vascular morphology, structure, and...
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Article
Open AccessThe classification of flash visual evoked potential based on deep learning
Visual electrophysiology is an objective visual function examination widely used in clinical work and medical identification that can objectively evaluate visual function and locate lesions according to wavefo...
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Article
Open AccessRetraction Note: A smart position optimization scheme for badminton doubles based on human–computer interactive training in wireless sensor networks
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Article
Open AccessThe long-term survival of the doublet regimen of concurrent chemoradiation therapy for locoregionally advanced nasopharyngeal carcinoma: a retrospective study
This study introduces innovative strategies, the doublet regimen of concurrent chemoradiotherapy, to ensure longer survival for locoregionally advanced nasopharyngeal carcinoma.
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Article
Open AccessReading activities compensate for low education-related cognitive deficits
The incidence of cognitive impairment is increasing with an aging population. Develo** effective strategies is essential to prevent dementia. Higher education level is associated with better baseline cogniti...
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Article
Open AccessEfficacy prediction of noninvasive ventilation failure based on the stacking ensemble algorithm and autoencoder
Early prediction of noninvasive ventilation failure is of great significance for critically ill ICU patients to escalate or change treatment. Because clinically collected data are highly time-series correlated...
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Article
Modeling and Analysis of Temperature Compensation for Multi-temperature Zone Sintering Furnace Temperature Sensing
The surface temperature of workpieces in a multi-temperature zone sintering furnace is an important parameter to characterize the performances of a multi-temperature zone system. Due to the practical structura...
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Article
Open AccessSingle-cell transcriptomic analysis of eutopic endometrium and ectopic lesions of adenomyosis
Adenomyosis (AM) is a common benign chronic gynaecological disorder; however, the precise pathogenesis of adenomyosis is still poorly understood. Single-cell RNA sequencing (scRNA-seq) can uncover rare subpopu...
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Article
Sn/Sn3O4−x heterostructure rich in oxygen vacancies with enhanced visible light photocatalytic oxidation performance
Sn3O4, a common two-dimensional semiconductor photocatalyst, can absorb visible light. However, owing to its rapid recombination of photogenerated electron-hole pairs, its absorption is not sufficient for practic...
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Article
Open AccessRETRACTED ARTICLE: A smart position optimization scheme for badminton doubles based on human–computer interactive training in wireless sensor networks
In the continuous development process, robot technology based on multimedia interactions has been widely used in aerospace, medical, education and service industries. The relationship between robots and humans...
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Article
The effect of spleen tyrosine kinase inhibitor R406 on diabetic retinopathy in experimental diabetic rats
To investigate the effect of spleen tyrosine kinase (Syk) inhibitor R406 on diabetic retinopathy (DR) in diabetic mellitus (DM) rats.
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Article
Molecular characterization of a novel botoulivirus from the phytopathogenic fungus Sclerotinia minor
In this study, the complete genomic sequence of a novel botoulivirus (Sclerotinia minor botoulivirus 1, SmBV1) from the phytopathogenic fungus Sclerotinia minor strain LC45 was determined. The genome of SmBV1 is ...
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Article
Open AccessAssociations of ACE I/D polymorphism with the levels of ACE, kallikrein, angiotensin II and interleukin-6 in STEMI patients
This study aimed to compare the plasma levels of angiotensin-I converting enzyme (ACE), Angiotensin II (AngII), kallikrein (KLK1) and interleukin-6 (IL-6) in ST segment elevation myocardial infarction (STEMI) ...
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Article
Open AccessPADI3 plays an antitumor role via the Hsp90/CKS1 pathway in colon cancer
CKS1 is highly expressed in colon cancer tissues, and is essential for cancer cell proliferation. The downstream molecular mechanism of CKS1 has been fully studied, but the upstream regulatory mechanism of it ...
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Open AccessPrenatal diagnosis of fetal skeletal dysplasia using targeted next-generation sequencing: an analysis of 30 cases
This study aims to provide genetic diagnoses for 30 cases of fetal skeletal dysplasia, and a molecular basis for the future prenatal diagnosis of fetal skeletal dysplasia.