-
Article
The Design of Hardened Case and Carburizing Process of Subway Gear Based on Spalling Fatigue
It is very important to design the suitable hardened case and carburizing-quenching process for gears. The hardened case was often determined by empirical data or the module (m) and lacked quantitative analysis. ...
-
Article
Open AccessSpatiotemporal dynamics of traffic bottlenecks yields an early signal of heavy congestions
Heavy traffic jams are difficult to predict due to the complexity of traffic dynamics. Understanding the network dynamics of traffic bottlenecks can help avoid critical large traffic jams and improve overall t...
-
Article
Tungsten-doped cobalt sulfide/selendie as high-efficient electrocatalyst for outstanding overall water splitting
The development of earth-abundant and highly efficient bifunctional electrocatalysts is a pressing requirement for electrochemical water splitting. However, several critical challenges still need to be address...
-
Article
Open AccessRapidly progressive interstitial lung disease combined with pneumocystis jiroveci pneumonia in a patient with single anti-TIF-1γ antibody positive dermatomyositis in the context of an underlying tumor
Interstitial lung disease (ILD) is a frequently observed comorbidity in autoimmune diseases such as dermatomyositis/polymyositis (DM/PM), and it is significantly associated with specific autoantibody types. On...
-
Article
Analysis and Optimization of Carburizing–Quenching Distortion on Locomotive Gear Ring
The carburizing–quenching distortion (CQD) of the gear ring is difficult to control, considering the heat transfer, phase transformation, and stress effects, so a numerical simulation model of the CQD on the l...
-
Article
Open AccessSubclinical diagnosis of cisplatin-induced ototoxicity with biomarkers
A mouse model with cisplatin-induced ototoxicity was used in addition to human samples from the ITMAT Biobank at the University of Pennsylvania. Mouse auditory brainstem responses (ABR), inner ear histology, p...
-
Article
Special issue: Reliability management of complex system
-
Article
Percolation-based health management of complex traffic systems
System health management, which aims to ensure the safe and efficient operation of systems by reducing uncertain risks and cascading failures during their lifetime, is proposed for complex transportation syste...
-
Article
Open AccessIOT security privacy protection mechanism and mechanical structure design simulation optimization
Once the Internet of Things was proposed, it has received great attention from all walks of life and has become one of the top ten technologies that change the world. Therefore, more and more people are engage...
-
Article
Open AccessSystematic and other reviews: criteria and complexities
-
Article
Selenium mitigates salt-induced oxidative stress in durum wheat (Triticum durum Desf.) seedlings by modulating chlorophyll fluorescence, osmolyte accumulation, and antioxidant system
Hydroponic experiments were conducted to investigate the effects of different concentrations of sodium selenate (Na2SeO4) and sodium selenite (Na2SeO3) on durum wheat seed germination and seedling growth under sa...
-
Article
Open AccessFake news propagates differently from real news even at early stages of spreading
Social media can be a double-edged sword for society, either as a convenient channel exchanging ideas or as an unexpected conduit circulating fake news through a large population. While existing studies of fak...
-
Article
Open AccessCochlear protein biomarkers as potential sites for targeted inner ear drug delivery
The delivery of therapies to the cochlea is notoriously challenging. It is an organ protected by a number of barriers that need to be overcome in the drug delivery process. Additionally, there are multiple sit...
-
Article
Open AccessPD-L1 and MRN synergy in platinum-based chemoresistance of head and neck squamous cell carcinoma
We have been investigating the molecular mechanisms of cisplatin-induced chemoresistance in head and neck squamous cell carcinoma (HNSCC). Based on our previous findings, the present study investigates how the...
-
Article
Open AccessAssociations of ACE I/D polymorphism with the levels of ACE, kallikrein, angiotensin II and interleukin-6 in STEMI patients
This study aimed to compare the plasma levels of angiotensin-I converting enzyme (ACE), Angiotensin II (AngII), kallikrein (KLK1) and interleukin-6 (IL-6) in ST segment elevation myocardial infarction (STEMI) ...
-
Article
Open AccessIdentifying the most influential roads based on traffic correlation networks
Prediction of traffic congestion is one of the core issues in the realization of smart traffic. Accurate prediction depends on understanding of interactions and correlations between different city locations. W...
-
Article
Open AccessGeneration of c-MycERTAM-transduced human late-adherent olfactory mucosa cells for potential regenerative applications
Human olfactory mucosa cells (hOMCs) have been transplanted to the damaged spinal cord both pre-clinically and clinically. To date mainly autologous cells have been tested. However, inter-patient variability i...
-
Article
Open AccessBioprocessing strategies to enhance the challenging isolation of neuro-regenerative cells from olfactory mucosa
Olfactory ensheathing cells (OECs) are a promising potential cell therapy to aid regeneration. However, there are significant challenges in isolating and characterizing them. In the current study, we have expl...
-
Article
The Development of a Nano-based Approach to Alleviate Cisplatin-Induced Ototoxicity
Cisplatin-induced hearing loss is experienced by a high percentage of patients with squamous cell carcinoma undergoing cisplatin chemotherapy. A novel nano-construct capable of sequestering extracellular cispl...
-
Article
Open AccessComparison of traffic reliability index with real traffic data
Existing studies have developed different indices based on various approaches including network connectivity, delay time and flow capacity, estimating the traffic reliability states from different angles. Howe...
