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Article
Open AccessHematopoietic stem and progenitor cell membrane-coated vesicles for bone marrow-targeted leukaemia drug delivery
Leukemia is a kind of hematological malignancy originating from bone marrow, which provides essential signals for initiation, progression, and recurrence of leukemia. However, how to specifically deliver drugs...
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Article
Comparing Mechanical and Oxidation Properties of Cr- and Si-Alloyed Press-Hardened Steel with 22MnB5 Steel at Various Heating Temperatures
High-performance press-hardened steels (PHS) are highly desired in automotive body-in-white due to their excellent strength and crashworthiness. PHS alloyed with high Cr and Si show promise in enhancing oxidat...
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Article
Open AccessElastic strain-induced amorphization in high-entropy alloys
Elastic stability is the basis for understanding structural responses to external stimuli in crystalline solids, including melting, incipient plasticity and fracture. In this work, elastic stability is investi...
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Article
Open AccessCorrelation between ovarian follicular development and Hippo pathway in polycystic ovary syndrome
For women of childbearing age, the biggest problem caused by polycystic ovary syndrome (PCOS) is infertility, which is mainly caused by anovulation, abnormal follicular development, proliferation of small antr...
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Article
Recent research progress on the phase-field model of microstructural evolution during metal solidification
Solidification structure is a key aspect for understanding the mechanical performance of metal alloys, wherein composition and casting parameters considerably influence solidification and determine the unique ...
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Article
Influence of Sulfur on the Splitting Fracture and Machining Performance of Microalloyed Medium-Carbon Steel 36MnVS4 Connecting Rods
The differences of 0.032% and 0.066% sulfur content on the splitting fracture and machining properties of microalloyed medium-carbon steel 36MnVS4 were studied. The splitting fracture and machining properties ...
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Article
Variant Pairing Quantification Method for a Bainitic HSLA Steel
Variant pairing describes the preference of variant pairs during displacive transformations. It is a decisive factor on the morphology and boundary characteristics of transformation products. Conventional vari...
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Article
Improved data-driven performance of Charpy impact toughness via literature-assisted production data in pipeline steel
Pipeline transportation is one of the most economical ways to transport crude oil and natural gas over long distances. High toughness is one of the important qualities of pipeline steel to ensure safe transpor...
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Article
Advances in machine learning- and artificial intelligence-assisted material design of steels
With the rapid development of artificial intelligence technology and increasing material data, machine learning- and artificial intelligence-assisted design of high-performance steel materials is becoming a ma...
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Article
Long-term fertilization enhances soil carbon stability by increasing the ratio of passive carbon: evidence from four typical croplands
Soil organic carbon (SOC) plays an important role in improving soil quality, however, how long-term fertilization influences SOC and contrasting active C (AC) and passive C (PC) pools at large scale remains un...
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Article
An Update on the International Society of Pharmacovigilance China Chapter
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Article
Open AccessPeptide nano-blanket impedes fibroblasts activation and subsequent formation of pre-metastatic niche
There is evidence to suggest that the primary tumor induces the formation of a pre-metastatic niche in distal organs by stimulating the production of pro-metastatic factors. Given the fundamental role of the p...
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Article
Contrasting responses of plant above and belowground biomass carbon pools to extreme drought in six grasslands spanning an aridity gradient
As global climate change intensifies, the frequency and duration of extreme droughts are predicted to increase, resulting in extended periods of reduced soil water availability across ecosystems. The allocatio...
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Article
Tribological properties of high-entropy alloys: A review
Tribology, which is the study of friction, wear, and lubrication, largely deals with the service performance of structural materials. For example, newly emerging high-entropy alloys (HEAs), which exhibit excel...
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Article
Changes in species abundances with short-term and long-term nitrogen addition are mediated by stoichiometric homeostasis
Increasing nitrogen (N) deposition has altered plant communities globally, however the changes in species abundances with short-term vs. long-term N enrichment remains unclear. Stoichiometric homeostasis, quan...
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Thresholds in decoupled soil-plant elements under changing climatic conditions
Aridity has increased in the past decades and will probably continue to increase in arid and semiarid regions. Here we decipher the plant and soil capacity to retain metal cations when climate evolves to more ...
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Article
Open AccessDivergent Effects of Nitrogen Addition on Soil Respiration in a Semiarid Grassland
Nitrogen (N) deposition has been steadily increasing for decades, with consequences for soil respiration. However, we have a limited understanding of how soil respiration responds to N availability. Here, we i...
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A threshold reveals decoupled relationship of sulfur with carbon and nitrogen in soils across arid and semi-arid grasslands in northern China
How climatic factors influence the balance of sulfur (S) with carbon (C) and nitrogen (N) in soils is not well understood. Here we report the results of S, C and N concentrations in 550 soil samples along a 35...
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Article
Open AccessLong term prevention of disturbance induces the collapse of a dominant species without altering ecosystem function
Limitation of disturbances, such as grazing and fire, is a key tool for nature reserve management and ecological restoration. While the role of these disturbances in sha** ecosystem structure and functioning...
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Article
Open AccessThe impact of the major causes of death on life expectancy in China: a 60-year longitudinal study
In the 12th Five-Year Plan, the Chinese government set the goal of increasing life expectancy by one year. The purpose of this study is to examine the impact of major causes of death on the life expectancy of ...
