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Article
Preparation and evaluation of 188Re-labeled octreotide analog in C6 glioma tumor
In the present study, preparation of [188Re]Re-Tricine-HYNIC-Tyr3-octreotide, stability in human serum, internalization, cell viability analysis, and in vivo tissue biodistribution in rats bearing C6 glioma tumor...
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Article
Assessment of Re/[99mTc]Tc-cirsiliol as a potential radiotracer to detect melanoma tumor
The purpose of this study was to label a trihydroxyflavone with the name of cirsiliol (3’,4’,5-Trihydroxy-6,7-dimethoxyflavone) with Re/[99mTc]Tc. After that in vivo study in C57 mice with Xenograft melanoma tumo...
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Article
Radiolabeling of zoledronic acid with 188Re as a new palliative agent radiotracer in treatment of bone tumors
Zoledronic acid is a bisphosphonates to treat bone problems. Rhenium-188-zoledronic acid could be used as a palliate agent in skeletal metastases. Radiolabeled product was prepared through optimized radiochemi...
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Article
Comparison of estimated human effective dose of 67Ga- and 99mTc-labeled bombesin based on distribution data in mice
This study describes the preparation, biodistribution and absorbed dose prediction of 67Ga and 99mTc labeled bombesin (BBN) in human organs, after injection in mice determined via medical internal radiation dose....
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Article
Preparation of a rhenium-188 labeled bisphosphonate for bone pain palliation therapy
In order to reduce the pain due bone metastases a last generation bisphosphonate, 2-(3-pyridinyl)-1-hydroxyethane diphosphonic acid, was labeled with 188Re and investigated further. Labeling was performed at 95 °...
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Article
Radioiodination of 4-benzyl-1-(3-iodobenzylsulfonyl)piperidine, 4-(3-iodobenzyl)-1-(benzylsulfonyl)piperazine and their derivatives via isotopic and non-isotopic exchange reactions
A mild and simple technique for preparing of 4-benzyl-1-(3-[125I]iodobenzylsulfonyl)piperidine, 4-(3-[125I]iodobenzyl)-1-(benzylsulfonyl)piperazine and their derivatives, as sigma-1 receptor ligands, with relativ...
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Article
Preparation and evaluation of a new neurotensin analog labeled with 99mTc for targeted imaging of neurotensin receptor positive tumors
Neurotensin receptors are overexpressed in several human tumors and can be targets for tumors diagnosis and therapy. In this study, a new neurotensin analogue was labeled with 99mTc via HYNIC and tricine/EDDA as ...
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Article
Preparation of 99mTc-MIBI complex under ultrasound irradiation
The (37MBq) 99mTc-MIBI complex samples were prepared due to ultrasound irradiation technique or boiled water bath method as a standard method. The qualitative and quantitative studies have been performed. The ...
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Article
99mTc-labeling of a dithiocarbamate-DWAY fragment using [99mTcN]2+ core for the preparation of potential 5HT1A receptor imaging agents
1-(2-methoxy phenyl) piperazine fragment of WAY100635 or its phenolic analogue, derived from DWAY is used to design the desired structure of 5HT1A receptor imaging agents. In this study a DWAY analogue was labele...