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Article
Preparation and validation of [67Ga]Ga-phytate kit and Monte Carlo dosimetry: an effort toward develo** an impressive lymphoscintigraphy tracer
Radiocolloides are essential for the detection of metastatic lymph nodes in breast cancer. In this study [67Ga]Ga-phytate, as an long-lived alternative for [99mTc]Tc-radiocolloids was prepared. "Standard" labelin...
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Article
Radiolabeling of Preformed Niosomes with [99mTc]: In Vitro Stability, Biodistribution, and In Vivo Performance
Nanocarriers radiolabeled with [99mTc] can be used for diagnostic imaging and radionuclide therapy, as well as tracking their pharmacokinetic and biodistribution characteristics. Due to the advantages of niosomes...
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Article
Erratum to: Development of a 68Ga-peptide tracer for PET GnRH1-imaging
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Article
Development of a 68Ga-peptide tracer for PET GnRH1-imaging
Total synthesis, quality control and preclinical evaluation of [68Ga]-DOTA-triptorelin ([68Ga]-DOTA-TRP) is reported as a possible PET radiotracer for GnRH receptor imaging.
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Article
Development of 166Ho-pamidronate for bone pain palliation therapy
In this work 166Ho labeled (3-amino-1-hydroxypropane-1,1-di-yl)-bis-(phosphonate) (166Ho-PMD) complex was prepared successfully at optimized conditions with acceptable radiochemical purity, stability and signific...
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Article
Radioiodination of 4-benzyl-1-(3-iodobenzylsulfonyl)piperidine, 4-(3-iodobenzyl)-1-(benzylsulfonyl)piperazine and their derivatives via isotopic and non-isotopic exchange reactions
A mild and simple technique for preparing of 4-benzyl-1-(3-[125I]iodobenzylsulfonyl)piperidine, 4-(3-[125I]iodobenzyl)-1-(benzylsulfonyl)piperazine and their derivatives, as sigma-1 receptor ligands, with relativ...
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Article
Open AccessPreparation and radiolabeling of a lyophilized (kit) formulation of DOTA-rituximab with 90Y and 111In for domestic radioimmunotherapy and radioscintigraphy of Non-Hodgkin’s Lymphoma
On the basis of results of our previous investigations on 90Y-DTPA-rituximab and in order to fulfil national demands to radioimmunoconjugates for radioscintigraphy and radioimmunotherapy of Non-Hodgkin’s Lymphoma...
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Article
Synthesis of novel tetra- and pentacyclic benzosultam scaffolds via domino Knoevenagel hetero-Diels–Alder reactions in water
An efficient catalyst-free and diastereoselective synthesis of novel dihydropyrano[2,3-d]pyrimidine and dihydropyrano[3,2-c]chromen-annulated benzosultams is described. A number of (E)-N-(2-formylphenyl)-N-methyl...
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Article
Biodistribution of ultra small superparamagnetic iron oxide nanoparticles in BALB mice
Recently ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles (NPs) have been widely used for medical applications. One of their important applications is using these particles as MRI contrast agent. ...
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Article
Comparison of 99mTc-labeled PR81 and its F(ab′)2 fragments as radioimmunoscintigraphy agents for breast cancer imaging
We digested anti-MUC1 monoclonal antibody PR81 to produce F(ab′)2 fragments. A comparison was performed between the two radiolabeled PR81 and F(ab′)2 fragments for breast tumor imaging in a mouse model.