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Article
Quantitative Effect of Magnetic Field Strength on PEGylated Superparamagnetic Iron Oxide Nanoparticles
With promising applications of superparamagnetic iron oxide nanoparticles (SPIO) in magnetic resonance imaging (MRI) and targeted monitoring of molecular and cellular processes, many different samples of these...
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Article
PEGylated superparamagnetic iron oxide nanoparticles labeled with 68Ga as a PET/MRI contrast agent: a biodistribution study
The purpose of this study is to evaluate the biodistribution of polyethylene glycol (PEG) coated superparamagnetic iron oxide nanoparticles radiolabeled with 68Ga in normal mice after intravenous administration o...
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Article
Preparation and biological assessment of 177Lu-BPAMD as a high potential agent for bone pain palliation therapy: comparison with 177Lu-EDTMP
In this study, 177Lu-(4-{[(bis(phosphonomethyl))carbamoyl]methyl}-7,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl) acetic acid (177Lu-BPAMD) was successfully prepared. The quality control, partition coef...
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Article
Biodistribution evaluation of 166Ho–DTPA–SPION in normal rats
Super paramagnetic iron oxide nanoparticles (SPION) with a cross-linked dextran coating can be used as a negative contrast agent in magnetic resonance imaging agent. This study describes the preparation, biod...
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Article
Comparison of estimated human dose of 68Ga-MAA with 99mTc-MAA based on rat data
99mTc macroaggregated albumin (99mTc-MAA) that had been used as a perfusion agent has been evaluated. In this study, we tried to estimate human absorbed dose of 68Ga-MAA via commercial...
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Article
Comparison of estimated human effective dose of 67Ga- and 99mTc-labeled bombesin based on distribution data in mice
This study describes the preparation, biodistribution and absorbed dose prediction of 67Ga and 99mTc labeled bombesin (BBN) in human organs, after injection in mice determined via medical internal radiation dose....
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Article
Estimated human absorbed dose for 68Ga-ECC based on mice data: comparison with 67Ga-ECC
Nowadays, the efficacies of 68Ga-based tracers are comparable to that of 18F-based agents and have stimulated researchers to investigate the potential of 68Ga-based positron emission tomography (PET) imaging agen...
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Article
Effect of Functional Group and Surface Charge of PEG and Dextran-Coated USPIO as a Contrast Agent in MRI on Relaxivity Constant
The challenges in molecular imaging are focused on the development of novel contrast agents with much lower relaxation times. Ultrasmall superparamagnetic iron oxide nanoparticles known as USPIO have been used...
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Article
Assessment of human effective absorbed dose of 67 Ga–ECC based on biodistribution rat data
In a diagnostic context, determination of absorbed dose is required before the introduction of a new radiopharmaceutical to the market to obtain marketing authorization from the relevant agencies. In this work...
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Article
Open AccessModified Gadonanotubes as a promising novel MRI contrasting agent
Carbon nanotubes (CNTs) are emerging drug and imaging carrier systems which show significant versatility. One of the extraordinary characteristics of CNTs as Magnetic Resonance Imaging (MRI) contrasting agent ...
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Article
Biodistribution of ultra small superparamagnetic iron oxide nanoparticles in BALB mice
Recently ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles (NPs) have been widely used for medical applications. One of their important applications is using these particles as MRI contrast agent. ...