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Article
Differential dysregulation of CREB and synaptic genes in transgenic Drosophila melanogaster expressing shaggy (GSK3), TauWT, or Amyloid-beta
Tau, Amyloid-beta (Aβ42), and Glycogen synthase kinase 3 (GSK3) contribute to synaptic dysfunction observed in Alzheimer's disease (AD), the most common form of dementia. In the current study, the effect of pan-n...
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Article
Anticancer Effects of AKBA on Glioblastoma Cancer Cells Through Modulating TWIST1 and FOXM1 Expression Levels
Glioblastoma multiforme (GBM) is a highly aggressive and poor prognosis brain tumor with about 12- to 18-month median survival period and high mortality rate in human. Glioma cells are able to disseminate and ...
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Article
Salvia officinalis Induces Apoptosis in Mammary Carcinoma Cells Through Alteration of Bax to Bcl-2 Ratio
Salvia officinalis L. (sage) is one of the herbal plants frequently used in traditional medicine. Anti carcinogenic property of sage extract and the fact that it does not show toxic effect on normal cells, make t...