28 Result(s)

Article

Toward nutrition improving outcome of critically ill patients: How to interpret recent feeding RCTs?

Although numerous observational studies associated underfeeding with poor outcome, recent randomized controlled trials (RCTs) have shown that early full nutritional support does not benefit critically ill pati...

Jan Gunst, Michael P. Casaer, Jean-Charles Preiser, Jean Reignier… in Critical Care (2023)

Article

Clinical nutrition issues in 2022: What is missing to trust supplemental parenteral nutrition (SPN) in ICU patients?

A multidisciplinary group of international physicians involved in the medical nutrition therapy (MNT) of adult critically ill patients met to discuss the value, role, and open questions regarding supplemental ...

Mette M. Berger, Rosa Burgos, Michael P. Casaer, Edoardo De Robertis… in Critical Care (2022)

Article

Correction to: Management of moderate to severe traumatic brain injury: an update for the intensivist

Geert Meyfroidt, Pierre Bouzat, Michael P. Casaer… in Intensive Care Medicine (2022)

Article

Aerobic exercise capacity in long-term survivors of critical illness: secondary analysis of the post-EPaNIC follow-up study

To evaluate aerobic exercise capacity in 5-year intensive care unit (ICU) survivors and to assess the association between severity of organ failure in ICU and exercise capacity up to 5-year follow-up.

Nathalie Van Aerde, Philippe Meersseman, Yves Debaveye… in Intensive Care Medicine (2021)

Article

Impact of tight glucose control on circulating 3-hydroxybutyrate in critically ill patients

Recent evidence suggests a potentially protective effect of increasing ketone body availability via accepting low macronutrient intake early after onset of critical illness. The impact of blood glucose control...

Jan Gunst, Astrid De Bruyn, Michael P. Casaer, Sarah Vander Perre… in Critical Care (2021)

Article

Targeted treatment of iron deficiency in prolonged critical illness: an opportunity to improve survival or not?

Jan Gunst, Greet Van den Berghe, Michael P. Casaer in Critical Care (2021)

Article

Clinical validation of precision medicine protocols: the last mile is the longest

Michael P. Casaer, Audrey De Jong, Anders Perner in Intensive Care Medicine (2021)

Article

The clinical potential of GDF15 as a “ready-to-feed indicator” for critically ill adults

Circulating growth-differentiation factor-15 (GDF15), a cellular stress marker, abruptly increases during critical illness, but its later time course remains unclear. GDF15 physiologically controls oral intake...

Lisa Van Dyck, Jan Gunst, Michaël P. Casaer, Bram Peeters, Inge Derese… in Critical Care (2020)

Article

Towards a fasting-mimicking diet for critically ill patients: the pilot randomized crossover ICU-FM-1 study

In two recent randomized controlled trials, withholding parenteral nutrition early in critical illness improved outcome as compared to early up-to-calculated-target nutrition, which may be explained by benefic...

Lisa Van Dyck, Ilse Vanhorebeek, Alexander Wilmer, An Schrijvers… in Critical Care (2020)

Article

Gastrointestinal dysfunction in the critically ill: a systematic sco** review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine

Gastrointestinal (GI) dysfunction is frequent in the critically ill but can be overlooked as a result of the lack of standardization of the diagnostic and therapeutic approaches. We aimed to develop a research...

Annika Reintam Blaser, Jean-Charles Preiser, Sonja Fruhwald… in Critical Care (2020)

Article

Metabolic support in the critically ill: a consensus of 19

Metabolic alterations in the critically ill have been studied for more than a century, but the heterogeneity of the critically ill patient population, the varying duration and severity of the acute phase of il...

Jan Wernerman, Kenneth B. Christopher, Djillali Annane, Michael P. Casaer… in Critical Care (2019)

Article

The soluble mannose receptor (sMR/sCD206) in critically ill patients with invasive fungal infections, bacterial infections or non-infectious inflammation: a secondary analysis of the EPaNIC RCT

Invasive fungal infections (IFI) are difficult to diagnose, especially in critically ill patients. As the mannose receptor (MR) is shed from macrophage cell surfaces after exposure to fungi, we investigate whe...

Greet De Vlieger, Ilse Vanhorebeek, Pieter J. Wouters, Inge Derese… in Critical Care (2019)

Article

Micronutrient deficiency in critical illness: an invisible foe?

Michael P. Casaer, Rinaldo Bellomo in Intensive Care Medicine (2019)

Article

Is protein intake saturated at doses recommended by the feeding guidelines for critically ill patients?

Jan Gunst, Michael P. Casaer in Critical Care (2018)

Article

Optimal guidance for early nutrition therapy in critical illness?

Michael P. Casaer, Jean Reignier, Gordon Doig in Intensive Care Medicine (2017)

Article

The intensive care medicine research agenda in nutrition and metabolism

The objectives of this review are to summarize the current practices and major recent advances in critical care nutrition and metabolism, review common beliefs that have been contradicted by recent trials, hig...

Yaseen M. Arabi, Michael P. Casaer, Marianne Chapman… in Intensive Care Medicine (2017)

Article

Early enteral nutrition in critically ill patients: ESICM clinical practice guidelines

To provide evidence-based guidelines for early enteral nutrition (EEN) during critical illness.

Annika Reintam Blaser, Joel Starkopf, Waleed Alhazzani… in Intensive Care Medicine (2017)