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  1. Article

    Open Access

    Statistical analysis plan for the replacing protein via enteral nutrition in a stepwise approach in critically ill patients (REPLENISH) randomized clinical trial

    The optimal amount and timing of protein intake in critically ill patients are unknown. REPLENISH (Replacing Protein via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients) trial evaluates whe...

    Yaseen M Arabi, Hasan M. Al-Dorzi, Omar Aldibaasi, Musharaf Sadat, Jesna Jose in Trials (2024)

  2. Article

    Open Access

    Replacing protein via enteral nutrition in a stepwise approach in critically ill patients: the REPLENISH randomized clinical trial protocol

    Protein intake is recommended in critically ill patients to mitigate the negative effects of critical illness-induced catabolism and muscle wasting. However, the optimal dose of enteral protein remains unknown...

    Yaseen M. Arabi, Hasan M. Al-Dorzi, Musharaf Sadat, Dina Muharib, Haifa Algethamy in Trials (2023)

  3. Article

    Open Access

    Toward nutrition improving outcome of critically ill patients: How to interpret recent feeding RCTs?

    Although numerous observational studies associated underfeeding with poor outcome, recent randomized controlled trials (RCTs) have shown that early full nutritional support does not benefit critically ill pati...

    Jan Gunst, Michael P. Casaer, Jean-Charles Preiser, Jean Reignier in Critical Care (2023)

  4. Article

    Open Access

    Association between early nutrition support and 28-day mortality in critically ill patients: the FRANS prospective nutrition cohort study

    Current guidelines suggest the introduction of early nutrition support within the first 48 h of admission to the intensive care unit (ICU) for patients who cannot eat. In that context, we aimed to describe nut...

    Emmanuel Pardo, Thomas Lescot, Jean-Charles Preiser, Pablo Massanet in Critical Care (2023)

  5. Article

    Open Access

    Effect of an enteral amino acid blend on muscle and gut functionality in critically ill patients: a proof-of-concept randomized controlled trial

    A defining feature of prolonged critical illness is muscle wasting, leading to impaired recovery. Supplementation with a tailored blend of amino acids may bolster the innate gut defence, promote intestinal muc...

    Nicholas Heming, Robert Carlier, Helene Prigent, Ahmed Mekki in Critical Care (2022)

  6. Article

    Machine-assisted nutritional and metabolic support

    Jean Reignier, Yaseen M. Arabi, Jean-Charles Preiser in Intensive Care Medicine (2022)

  7. Article

    Open Access

    Intravenous vitamin C in adults with sepsis in the intensive care unit: still LOV’IT?

    Christian Stoppe, Jean-Charles Preiser, Daniel de Backer, Gunnar Elke in Critical Care (2022)

  8. Article

    Open Access

    Impact of prolonged requirement for insulin on 90-day mortality in critically ill patients without previous diabetic treatments: a post hoc analysis of the CONTROLING randomized control trial

    Stress hyperglycemia can persist during an intensive care unit (ICU) stay and result in prolonged requirement for insulin (PRI). The impact of PRI on ICU patient outcomes is not known. We evaluated the relatio...

    François Thouy, Julien Bohé, Bertrand Souweine, Hassane Abidi in Critical Care (2022)

  9. No Access

    Article

    Individualized glycaemic management for critically ill patients. Authors’ reply

    Julien Bohé, Jean-Charles Preiser in Intensive Care Medicine (2022)

  10. Article

    Open Access

    A guide to enteral nutrition in intensive care units: 10 expert tips for the daily practice

    The preferential use of the oral/enteral route in critically ill patients over gut rest is uniformly recommended and applied. This article provides practical guidance on enteral nutrition in compliance with re...

    Jean-Charles Preiser, Yaseen M. Arabi, Mette M. Berger, Michael Casaer in Critical Care (2021)

  11. Article

    Open Access

    Individualised versus conventional glucose control in critically-ill patients: the CONTROLING study—a randomized clinical trial

    Hyperglycaemia is an adaptive response to stress commonly observed in critical illness. Its management remains debated in the intensive care unit (ICU). Individualising hyperglycaemia management, by targeting ...

    Julien Bohé, Hassane Abidi, Vincent Brunot, Amna Klich in Intensive Care Medicine (2021)

  12. Article

    Open Access

    Long-term outcomes after critical illness: recent insights

    Intensive care survivors often experience post-intensive care sequelae, which are frequently gathered together under the term “post-intensive care syndrome” (PICS). The consequences of PICS on quality of life,...

    Anne-Françoise Rousseau, Hallie C. Prescott, Stephen J. Brett, Björn Weiss in Critical Care (2021)

  13. Article

    Open Access

    Biomarkers in critical care nutrition

    The goal of nutrition support is to provide the substrates required to match the bioenergetic needs of the patient and promote the net synthesis of macromolecules required for the preservation of lean mass, or...

    Christian Stoppe, Sebastian Wendt, Nilesh M. Mehta, Charlene Compher in Critical Care (2020)

  14. Article

    Open Access

    Gastrointestinal dysfunction in the critically ill: a systematic sco** review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine

    Gastrointestinal (GI) dysfunction is frequent in the critically ill but can be overlooked as a result of the lack of standardization of the diagnostic and therapeutic approaches. We aimed to develop a research...

    Annika Reintam Blaser, Jean-Charles Preiser, Sonja Fruhwald in Critical Care (2020)

  15. No Access

    Article

    Dynamic properties of glucose complexity during the course of critical illness: a pilot study

    Methods to control the blood glucose (BG) levels of patients in intensive care units (ICU) improve the outcomes. The development of continuous BG levels monitoring devices has also permitted to optimize these ...

    Emmanuel Godat, Jean-Charles Preiser in Journal of Clinical Monitoring and Computi… (2020)

  16. No Access

    Chapter

    Nutritional Rehabilitation in the ICU

    At the end of this chapter, you should have learned much more about:

    Pablo Lucas Massanet, Thomas Lescot, Jean-Charles Preiser in Post-Intensive Care Syndrome (2020)

  17. No Access

    Chapter

    Feasibility of Follow-Up Consultations

    Health technology improvements lead to an increasing number of intensive care unit (ICU) survivors. However, long-term consequence interventions performed in ICUs may impact the patients’ quality of life. The ...

    Danielle Heloisa Prevedello, Jean-Charles Preiser in Post-Intensive Care Syndrome (2020)

  18. No Access

    Article

    Updates in Glycemic Management in the Hospital

    To provide an update of glycemic management during metabolic stress related to surgery or critical illness.

    Wasineenart Mongkolpun, Bruna Provenzano, Jean-Charles Preiser in Current Diabetes Reports (2019)

  19. Article

    Less is more in nutrition: critically ill patients are starving but not hungry

    Yaseen M. Arabi, Annika Reintam Blaser, Jean-Charles Preiser in Intensive Care Medicine (2019)

  20. Article

    Open Access

    Metabolic support in the critically ill: a consensus of 19

    Metabolic alterations in the critically ill have been studied for more than a century, but the heterogeneity of the critically ill patient population, the varying duration and severity of the acute phase of il...

    Jan Wernerman, Kenneth B. Christopher, Djillali Annane, Michael P. Casaer in Critical Care (2019)

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