-
Article
Open AccessBiomarkers In Prediction of Acute Mesenteric Ischaemia: a prospective multicentre study (BIPAMI study): a study protocol
Acute mesenteric ischaemia (AMI) is a life-threatening disease where early diagnosis is critical to avoid morbidity and mortality from extensive irreversible bowel necrosis. Appropriate prediction of presence ...
-
Article
Open AccessStatistical analysis plan for the replacing protein via enteral nutrition in a stepwise approach in critically ill patients (REPLENISH) randomized clinical trial
The optimal amount and timing of protein intake in critically ill patients are unknown. REPLENISH (Replacing Protein via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients) trial evaluates whe...
-
Article
Open AccessThe incidences of acute mesenteric ischaemia vary greatly depending on the population and diagnostic activity
-
Article
Open AccessVariation in Severity-Adjusted Resource use and Outcome for Neurosurgical Emergencies in the Intensive Care Unit
The correlation between the standardized resource use ratio (SRUR) and standardized hospital mortality ratio (SMR) for neurosurgical emergencies is not known. We studied SRUR and SMR and the factors affecting ...
-
Article
Open AccessIncidence, diagnosis, management and outcome of acute mesenteric ischaemia: a prospective, multicentre observational study (AMESI Study)
The aim of this multicentre prospective observational study was to identify the incidence, patient characteristics, diagnostic pathway, management and outcome of acute mesenteric ischaemia (AMI).
-
Article
Open AccessDiagnostic accuracy of biomarkers to detect acute mesenteric ischaemia in adult patients: a systematic review and meta-analysis
Acute mesenteric ischaemia (AMI) is a disease with different pathophysiological mechanisms, leading to a life-threatening condition that is difficult to diagnose based solely on clinical signs. Despite widely ...
-
Article
Open AccessReplacing protein via enteral nutrition in a stepwise approach in critically ill patients: the REPLENISH randomized clinical trial protocol
Protein intake is recommended in critically ill patients to mitigate the negative effects of critical illness-induced catabolism and muscle wasting. However, the optimal dose of enteral protein remains unknown...
-
Article
Acute abdominal pain at referral emergency departments: an analysis of performance of three time-dependent quality indicators
Abdominal pain is one of the most frequent causes for emergency department (ED) visits. The quality of care and outcomes are determined by time-dependent interventions with barriers to implementation at crowde...
-
Article
Associations between elevated high-sensitive cardiac troponin t and outcomes in patients with acute abdominal pain
The purpose of this study was to determine outcomes in patients presenting to emergency department (ED) with acute abdominal pain and suspected occult myocardial injury [OMI (high-sensitive cardiac troponin T,...
-
Article
Cardiovascular SOFA score may not reflect current practice
-
Chapter
Gastrointestinal Failure, Clinical Presentations, and Treatment
Gastrointestinal (GI) dysfunction is thought to be a motor of multiple organ dysfunction syndrome (MODS), but not included in scoring systems commonly used for MODS. One of the reasons for this contradiction i...
-
Article
Open AccessRemote ischaemic preconditioning influences the levels of acylcarnitines in vascular surgery: a randomised clinical trial
Vascular surgery patients have reduced tissues` blood supply, which may lead to mitochondrial dysfunction and accumulation of acylcarnitines (ACs). It has been suggested that remote ischaemic preconditioning (...
-
Article
Open AccessGastrointestinal dysfunction in the critically ill: a systematic sco** review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine
Gastrointestinal (GI) dysfunction is frequent in the critically ill but can be overlooked as a result of the lack of standardization of the diagnostic and therapeutic approaches. We aimed to develop a research...
-
Article
Open AccessP55 Remote Ischaemic Preconditioning Reduces Cardiac Biomarkers During Vascular Surgery
The primary aim of this study was to evaluate the effects of remote ischaemic preconditioning (RIPC) on preventing the leakage of cardiac damage biomarkers in patients undergoing vascular surgery.
-
Article
Open AccessGenetic variants in humanin nuclear isoform gene regions show no association with coronary artery disease
Coronary artery disease contributes to noncommunicable disease deaths worldwide. In order to make preventive methods more accurate, we need to know more about the development and progress of this pathology, in...
-
Article
Open AccessP65 Remote Ischaemic Preconditioning Reduces Kidney Injury in Vascular Surgery
Perioperative acute kidney injury has been found to occur in 12% of patients undergoing lower limb revascularisation (Arora et al., 2013). The aim of the current double-blinded, randomised and shamcontrolled p...
-
Article
Open AccessEarly enteral nutrition in critically ill patients: ESICM clinical practice guidelines
To provide evidence-based guidelines for early enteral nutrition (EEN) during critical illness.
-
Article
Open AccessSpace GlucoseControl system for blood glucose control in intensive care patients - a European multicentre observational study
Glycaemia control (GC) remains an important therapeutic goal in critically ill patients. The enhanced Model Predictive Control (eMPC) algorithm, which models the behaviour of blood glucose (BG) and insulin sen...
-
Article
Open AccessRisk factors for intra-abdominal hypertension and abdominal compartment syndrome among adult intensive care unit patients: a systematic review and meta-analysis
Although intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are associated with substantial morbidity and mortality among critically ill adults, it remains unknown if prevention or tre...
-
Article
Open AccessGastrointestinal symptoms during the first week of intensive care are associated with poor outcome: a prospective multicentre study
The study aimed to develop a gastrointestinal (GI) dysfunction score predicting 28-day mortality for adult patients needing mechanical ventilation (MV).
