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  1. Article

    Open Access

    Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function

    Mesenchymal stromal cells (MSCs) are renoprotective and drive regeneration following injury, although cellular targets of such an effect are still ill-defined. Here, we show that human umbilical cord (UC)-MSCs...

    Luca Perico, Marina Morigi, Cinzia Rota, Matteo Breno in Nature Communications (2017)

  2. Article

    Open Access

    Extracellular vesicles derived from T regulatory cells suppress T cell proliferation and prolong allograft survival

    We have previously shown that rat allogeneic DC, made immature by adenoviral gene transfer of the dominant negative form of IKK2, gave rise in-vitro to a unique population of CD4+CD25 regulatory T cells (dnIKK2-...

    Sistiana Aiello, Federica Rocchetta, Lorena Longaretti in Scientific Reports (2017)