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  1. Article

    Open Access

    Therapeutic potential of stromal cells of non-renal or renal origin in experimental chronic kidney disease

    Mesenchymal stromal cell (MSC)-based therapy is a promising strategy for preventing the progression of chronic kidney disease (CKD), with the potential to induce tissue regeneration. In search of the best cell...

    Cinzia Rota, Marina Morigi, Domenico Cerullo… in Stem Cell Research & Therapy (2018)

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  2. Article

    Open Access

    Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function

    Mesenchymal stromal cells (MSCs) are renoprotective and drive regeneration following injury, although cellular targets of such an effect are still ill-defined. Here, we show that human umbilical cord (UC)-MSCs...

    Luca Perico, Marina Morigi, Cinzia Rota, Matteo Breno… in Nature Communications (2017)

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  3. Article

    Open Access

    A previously unrecognized role of C3a in proteinuric progressive nephropathy

    Podocyte loss is the initial event in the development of glomerulosclerosis, the structural hallmark of progressive proteinuric nephropathies. Understanding mechanisms underlying glomerular injury is the key c...

    Marina Morigi, Monica Locatelli, Cinzia Rota, Simona Buelli… in Scientific Reports (2016)

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  4. No Access

    Protocol

    Mesenchymal Stem Cells in Kidney Repair

    Every year 13.3 million people suffer acute kidney injury (AKI), which is associated with a high risk of death or development of long-term chronic kidney disease (CKD) in a substantial percentage of patients b...

    Marina Morigi Ph.D., Cinzia Rota, Giuseppe Remuzzi in Mesenchymal Stem Cells (2016)