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Article

Extracellular vesicles derived from T regulatory cells suppress T cell proliferation and prolong allograft survival

We have previously shown that rat allogeneic DC, made immature by adenoviral gene transfer of the dominant negative form of IKK2, gave rise in-vitro to a unique population of CD4⁺CD25⁻ regulatory T cells (dnIKK2-...

Sistiana Aiello, Federica Rocchetta, Lorena Longaretti… in Scientific Reports (2017)