4 Result(s)

Article

CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage

The BH3-only protein NOXA is a regulator of mitochondrial apoptosis by specifically antagonizing the anti-apoptotic protein MCL-1. Here we show that the E3 ubiquitin ligase CHIP controls NOXA stability after D...

Marie-Christine Albert, Kerstin Brinkmann, Wojciech Pokrzywa… in Cell Death & Disease (2020)

Article

Therapeutic concentrations of antibiotics inhibit Shiga toxin release from enterohemorrhagic E. coli O104:H4 from the 2011 German outbreak

The shiga toxin-producing E. coli (STEC) O104:H4 caused a major outbreak in Germany in spring 2011. STEC are usually susceptible to common antibiotics. However, antibiotic treatment of STEC-infected patients is n...

Diana Corogeanu, Ruben Willmes, Martina Wolke, Georg Plum… in BMC Microbiology (2012)

Article

NOX enzymes as drug targets

Karl-Heinz Krause, David Lambeth, Martin Krönke in Cellular and Molecular Life Sciences (2012)

Article

Large scale multiplex PCR improves pathogen detection by DNA microarrays

Medium density DNA microchips that carry a collection of probes for a broad spectrum of pathogens, have the potential to be powerful tools for simultaneous species identification, detection of virulence factor...

Maria Palka-Santini, Berit E Cleven, Ludwig Eichinger, Martin Krönke… in BMC Microbiology (2009)