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Article
Extinction and Renewal of Conditioned Eyeblink Responses in Focal Cerebellar Disease
Extinction of conditioned aversive responses (CR) has been shown to be context-dependent. The hippocampus and prefrontal cortex are of particular importance. The cerebellum may contribute to context-related pr...
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Article
Structural correlates of motor adaptation deficits in patients with acute focal lesions of the cerebellum
Studies of cerebellar patients employing modern lesion-symptom map** techniques have provided valuable insights into the contribution of the cerebellum to motor adaptation. In patients with chronic focal les...
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Article
Open AccessNiche-dependent development of functional neuronal networks from embryonic stem cell-derived neural populations
The present work was performed to investigate the ability of two different embryonic stem (ES) cell-derived neural precursor populations to generate functional neuronal networks in vitro. The first ES cell-derive...
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Article
Aldolase C/Zebrin II is Released to the Extracellular Space after Stroke and Inhibits the Network Activity of Cortical Neurons
Cell death after stroke involves apoptotic, autophagocytic and necrotic mechanisms which may cause the release of cytosolic proteins to the extracellular space. Aldolase C (AldC) is the brain specific isoform ...
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Article
Cooperative effects of neuronal ensembles
Electrophysiological properties of neurons as the basic cellular elements of the central nervous system and their synaptic connections are well characterized down to a molecular level. However, the behavior of...