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within M. H. Ellisman Remove this filter Apoptosis Remove this filter

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  1. Article

    Cerium oxide nanoparticles protect against Aβ-induced mitochondrial fragmentation and neuronal cell death

    Evidence indicates that nitrosative stress and mitochondrial dysfunction participate in the pathogenesis of Alzheimer’s disease (AD). Amyloid beta (Aβ) and peroxynitrite induce mitochondrial fragmentation and neu...

    J M Dowding, W Song, K Bossy, A Karakoti, A Kumar, A Kim… in Cell Death & Differentiation (2014)

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  2. Article

    Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity

    Optic atrophy 1 ( OPA1 ) mutations cause dominant optic atrophy (DOA) with retinal ganglion cell (RGC) and optic nerve degeneration. The mechanism for the selectiv...

    Y E Kushnareva, A A Gerencser, B Bossy, W-K Ju, A D White… in Cell Death & Differentiation (2013)

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  3. Article

    Genetic variance modifies apoptosis susceptibility in mature oocytes via alterations in DNA repair capacity and mitochondrial ultrastructure

    Although the identification of specific genes that regulate apoptosis has been a topic of intense study, little is known of the role that background genetic variance plays in modulating cell death. Using germ ...

    G I Perez, B M Acton, A Jurisicova, G A Perkins, A White… in Cell Death & Differentiation (2007)

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  4. Article

    Mitochondria frozen with trehalose retain a number of biological functions and preserve outer membrane integrity

    In apoptosis, Bcl-2-family proteins regulate the barrier function of the mitochondrial outer membrane (MOM), controlling the release of proapoptotic proteins from the intermembrane space into the cytoplasm. Th...

    R Yamaguchi, A Andreyev, A N Murphy, G A Perkins… in Cell Death & Differentiation (2007)

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