8,816 Result(s)

Article

Expression of Concern to: RAGE-binding S100A8/A9 promotes the migration and invasion of human breast cancer cells through actin polymerization and epithelial–mesenchymal transition

Chonggao Yin, Hongli Li, Baogang Zhang, Yuqing Liu… in Breast Cancer Research and Treatment (2024)

Article

ASO Visual Abstract: Palliative Surgery for Patients with Gastroesophageal Junction or Gastric Cancer—A Report on Clinical Observational Outcomes

Yun Song MD, Eunise Chen BS, Naruhiko Ikoma MD, MS… in Annals of Surgical Oncology (2024)

Article

Effectiveness of gonadotropin-releasing hormone agonists for ovarian function suppression in premenopausal patients with hormone receptor-positive breast cancer: a retrospective single-center real-world study

This study evaluated the effectiveness of ovarian function suppression (OFS) of various gonadotropin-releasing hormone agonists (GnRHa) combined with aromatase inhibitors (AI) in premenopausal patients with ho...

Yifei Chen, Ruyan Zhang, Ying Yan, Hui** Li… in Breast Cancer Research and Treatment (2024)

Article

The Effect of Neoadjuvant Systemic Therapy on Surgical Outcomes After Lymph Node Dissections for Stage III Melanoma; An Australian Cohort

Neoadjuvant systemic therapy (NAST) for patients with stage III melanoma achieves high major pathologic response rates and high recurrence-free survival rates. This study aimed to determine how NAST with targe...

Lisanne P. Zijlker MD, Henry Chen BSc… in Annals of Surgical Oncology (2024)

Article

Adjuvant Chemoradiation in Resected Biliary Adenocarcinoma: Evaluation of SWOG S0809 with a Large National Database

There is a paucity of evidence supporting the use of adjuvant radiation therapy in resected biliary cancer. Supporting evidence for use comes mainly from the small SWOG S0809 trial, which demonstrated an overa...

Dana A. Dominguez MD, Paul Wong BS, Yi-Jen Chen MD, PhD… in Annals of Surgical Oncology (2024)

Article

Pedigree analysis exploring the inconsistency between diverse phenotypes and testing criteria for germline TP53 mutations in Chinese women with breast cancer

In the present study, we addressed the inconsistency between the testing criteria and diverse phenotypes for germline TP53 mutation in patients with breast cancer in the Chinese population.

**n Huang, Chang Chen, Yan Lin, Changjun Wang… in Breast Cancer Research and Treatment (2024)

Article

Synergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases

Mitotic catastrophe (MC), which occurs under dysregulated mitosis, represents a fascinating tactic to specifically eradicate tumor cells. Whether pyroptosis can be a death form of MC remains unknown. Proteasom...

Zhan-Li Chen, Chen **e, Wei Zeng, Rui-Qi Huang… in Signal Transduction and Targeted Therapy (2024)

Article

An analysis of the role of GAB2 in pan-cancer from a multidimensional perspective

To explore the role of GAB2 in pan-cancer based on bioinformatics analysis.

Yi Yin, Yong Li, Yaoyang Zhang, Qiucheng Jia, Huiming Tang… in Discover Oncology (2024)

Article

Correction: Apatinib combined with temozolomide in diffuse midline glioma: a novel and effective therapy

Yu-An Li, Chuan Zhao, **g-**g Ge, Cheng Li, Feng-Jun Xue, Shao-Pei Qi… in BMC Cancer (2024)

Article

Survival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: a nationwide registry study

Most gastrointestinal stromal tumors (GISTs) harbor c-KIT or PDGFRA mutations. Administration of tyrosine kinase inhibitors (TKIs) has significantly improved the survival of patients with GISTs. We aimed to evalu...

Hui-Jen Tsai, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai… in BMC Cancer (2024)

Article

N⁶-methyladenosine modification of circMARK2 enhances cytoplasmic export and stabilizes LIN28B, contributing to the progression of Wilms tumor

The potential involvement of circular RNAs (circRNAs) and N⁶-methyladenosine (m⁶A) modification in the progression of Wilms tumor (WT) has not been fully elucidated. This study investigates the regulatory mechani...

Guannan Shu, Zhang Zhao, Tianxin Zhao… in Journal of Experimental & Clinical Cancer … (2024)

Article

Associations between modifiable risk factors and hepatocellular carcinoma: a trans-ancestry Mendelian randomization study

Potentially modifiable risk factors for hepatocellular carcinoma (HCC) have been investigated in observational epidemiology studies in East Asian and European populations, whereas the causal associations of mo...

**aoxia Wei, Chenglei Yang, Qiuling Lin, Moqin Qiu, Qiu** Wen, Zihan Zhou… in BMC Cancer (2024)

Article

Mitochondrial DNA Copy Number as a Biomarker for Guiding Adjuvant Chemotherapy in Stages II and III Colorectal Cancer Patients with Mismatch Repair Deficiency: Seeking Benefits and Avoiding Harms

Colorectal cancer (CRC) patients with mismatch repair-deficient/microsatellite instability-high (dMMR/MSI-H) status are conventionally perceived as unresponsive to adjuvant chemotherapy (ACT). The mitochondria...

Mian Chen PhD, Shenghe Deng MD, Yinghao Cao MD, Jun Wang PhD… in Annals of Surgical Oncology (2024)

Article

A positive feedback loop between PFKP and c-Myc drives head and neck squamous cell carcinoma progression

The aberrant expression of phosphofructokinase-platelet (PFKP) plays a crucial role in the development of various human cancers by modifying diverse biological functions. However, the precise molecular mechani...

Weiwei Liu, Zhao Ding, Ye Tao, Shixian Liu, Maoyu Jiang, Fangzheng Yi… in Molecular Cancer (2024)

Article

Analysis of tumor abnormal protein expression and epidermal growth factor receptor mutation status in non-small cell lung cancer

The level of tumor abnormal protein (TAP) level has a significant impact on tumor growth, recurrence, and metastasis. Previous studies have highlighted the influence of the mutations in exons 19 and 21 of the ...

Yuanjun Cheng, Bin Chen, Qianru Fang, Guohui Zang, Jie Yao in Discover Oncology (2024)

Article

Study of sex-biased differences in genomic profiles in East Asian hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is characterized by a notable sex disparity in incidence and tumor aggressiveness. Revealing differences in genetic landscapes between male and female HCCs may expand the underst...

Chung-Yu Huang, Kien-Thiam Tan, Shiu-Feng Huang, Yen-Jung Lu… in Discover Oncology (2024)

Article

Analysis of the immune-inflammatory indices for patients with metastatic hormone-sensitive and castration-resistant prostate cancer

Inflammation plays a pivotal role in the progression of prostate cancer (PCa). Several immune-inflammatory indices, including neutrophil to lymphocyte ratio (NLR), derived neutrophil to lymphocyte ratio (dNLR)...

Zhipeng Wang, Haoyang Liu, Qiyu Zhu, Junru Chen, **ge Zhao, Hao Zeng in BMC Cancer (2024)

Article

Association of body composition indicators with colorectal cancer: a hospital-based case-control study

Colorectal cancer (CRC) is a common malignancy that affects adults worldwide, causing a high disease burden. Few studies have examined the relationship between body composition (BC) measures and the prevalence...

Qiu** Chen, Kai Li, Yang Liu, **aozhai Yu… in Journal of Cancer Research and Clinical On… (2024)

Article

Recursive partitioning analysis for survival stratification and early imaging prediction of molecular biomarker in glioma patients

Glioma is the most common primary brain tumor with high mortality and disability rates. Recent studies have highlighted the significant prognostic consequences of subty** molecular pathological markers using...

**an **e, Chen Luo, Shuai Wu, Wanyu Qiao, Wei Deng, Lei **, Junfeng Lu… in BMC Cancer (2024)

Article

Multi-omics differences in the bone marrow between essential thrombocythemia and prefibrotic primary myelofibrosis

Essential thrombocythemia (ET) and prefibrotic primary myelofibrosis (pre-PMF) are Philadelphia chromosome-negative myeloproliferative neoplasms. These conditions share overlap** clinical presentations; howe...

Anqi Zhang, Ting Sun, Dandan Yu, Rongfeng Fu… in Clinical and Experimental Medicine (2024)