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Article
Early and late hemopoietic precursor cells in patients with chronic myeloproliferative diseases
We evaluated the content of early and late cobblestone area-forming cells, immediate progeny of hemopoietic stem cells, and committed precursor cells in the bone marrow and peripheral blood of patients with ch...
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Article
In Vivo Production of Cytokines by Bone Marrow Stromal Cells and Macrophages from Patients with Myelodysplastic Syndrome
We studied functional disturbances in hemopoietic microenvironment and cytokine production by stromal sublayer in long-term bone marrow cultures and peripheral blood macrophages from patients with various form...
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Article
Functional disturbances in hemopoietic microenvironment in various forms of myelodysplastic syndrome
We studied the ability of stromal sublayer of long-term bone marrow cultures and peripheral blood macrophages from patients with various forms of myelodysplastic syndrome to maintain the growth of normal granu...
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Article
Functional disturbances in hemopoietic microenvironment in various forms of myelodysplastic syndrome
We studied the ability of stromal sublayer of long-term bone marrow cultures and peripheral blood macrophages from patients with various forms of myelodysplastic syndrome to maintain the growth of normal granu...
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Article
Changes in the hemopoietic system of mice deficient for tumor necrosis factor or lymphotoxin-α
Hemopoietic and stromal precursor cells were studied in mice deficient for tumor necrosis factor or lymphotoxin-α. In normal hemopoiesis the main characteristics of hemopoiesis in knockout mice did not differ ...
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Article
Kinetics of hemopoietic clones in sublethally irradiated mice
Hemopoiesis in sublethally irradiated mice is provided by a succession of clones of hemopoietic cells containing unique radioactive markers. Dozens of clones with short life-span (not more than 4 months) are f...
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Article
Functional activity of hemopoietic and stromal cells in various types of myelodysplastic syndrome
Using clonal methods for assessment of hemopoietic and stromal cells and long-term bone marrow cell cultures, we have demonstrated heterogeneity of myelodysplastic syndrome. Low content of stromal precursor ce...
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Article
Production of A B cell lymphoblastoid line from long-term human bone marrow suspension culture
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Article
Hematopoiesis in human embryonic liver organ culture
It was shown by the method of multiple organ cultures on Millipore filters that hematopoiesis of predominantly erythroid type is maintained for a long time (over 1.5 months) in cultures of human embryonic live...
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Article
Cultivation of human peripheral blood leukocytes in agar gel
The use of a modified method of cloning hematopoietic cells in semisolid nutrient media showed that among human peripheral blood leukocytes there are committed precursor cells of the granulocytic series (CFUc). I...