Abstract
Hemopoiesis in sublethally irradiated mice is provided by a succession of clones of hemopoietic cells containing unique radioactive markers. Dozens of clones with short life-span (not more than 4 months) are functioning during mouse life. Ten percent of these clones are long-lived and can be revealed during 20 months. These clones are formed exclusively by bone marrow stem cells in the G0-period of the cell cycle. A new structure of hemopoietic stem cell population is discussed.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 6, pp. 693–696, June, 1999
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Ol'shanskaya, Y.V., Gerasimova, L.P., Drize, N.I. et al. Kinetics of hemopoietic clones in sublethally irradiated mice. Bull Exp Biol Med 127, 633–636 (1999). https://doi.org/10.1007/BF02433300
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DOI: https://doi.org/10.1007/BF02433300