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Article
Instruments to Assess Cognitive Reserve Among Older Adults: a Systematic Review of Measurement Properties
Cognitive reserve explains the differences in the susceptibility to cognitive impairment related to brain aging, pathology, or insult. Given that cognitive reserve has important implications for the cognitive ...
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Article
The effects of incorporation of the counterparts and mimics of l-lysine on the antimicrobial activity, hemolytic activity, cytotoxicity and tryptic stability of antimicrobial peptide polybia-MPII
Due to the limited effects of conventional antibiotics on the increasing emergence of drug-resistant bacteria and fungi, novel antimicrobial agents were urgently needed to alleviate this phenomenon. Nowadays, ...
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Article
Tryptic Stability and Antimicrobial Activity of the Derivatives of Polybia-CP with Fine-Tuning Modification in the Side Chain of Lysine
Antimicrobial peptides (AMPs) were believed to be a class of promising antimicrobials to combat the increasing resistant microbes. However, AMPs could be easily degraded by endogenous proteases, which limited ...
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Article
The introduction of l-phenylalanine into antimicrobial peptide protonectin enhances the selective antibacterial activity of its derivative phe-Prt against Gram-positive bacteria
Protonectin was a typical amphiphilic antimicrobial peptide with potent antimicrobial activity against Gram-positive and Gram-negative bacteria. In the present study, when its eleventh amino acid in the sequen...
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Article
Open AccessQuality appraisal of gestational diabetes mellitus guidelines with AGREE II: a systematic review
Several societies and associations have produced and disseminated clinical practice guidelines (CPGs) for gestational diabetes mellitus (GDM). However, the quality of such guidelines has not been appraised so ...
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Article
Open AccessCurrent guidelines on the management of gestational diabetes mellitus: a content analysis and appraisal
Despite many guidelines for the management of gestational diabetes available internationally, little work has been done to summarize and assess the content of existing guidelines. A paucity of analysis guideli...
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Article
Preparation and characterization of a novel graphene/biochar composite and its application as an adsorbent for Cd removal from aqueous solution
A novel graphene/biochar composite (BG composite) was synthesized by mixing graphene (Gr) onto feedstock biomass followed by slow pyrolysis. The composite was then tested for its sorption capacity of Cd from a...
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Article
Contribution of root uptake to cadmium accumulation in two peanut cultivars: evidence from a split-column soil experiment
Cadmium (Cd) accumulation and internal Cd translocation in the peanut (Arachis hypogaea L.) are highly related to root uptake, which may largely depend on the cultivar variation and the depth of the Cd-contaminat...
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Article
Influence of Proline Substitution on the Bioactivity of Mammalian-Derived Antimicrobial Peptide NK-2
Multidrug-resistant bacteria are emerging as a global threat, making the search for alternative compounds urgent. Antimicrobial peptides (AMPs) became a promising hotspot due to their distinct action mechanism...
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Article
The in vitro, in vivo antifungal activity and the action mode of Jelleine-I against Candida species
Recently, the mortality of life-threatening fungal infections increased dramatically. However, there are few antifungals existed. Antimicrobial peptides (AMPs) as promising antifungal candidates have attracted...
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Article
Open AccessAntimicrobial activity and stability of the d-amino acid substituted derivatives of antimicrobial peptide polybia-MPI
Antimicrobial peptide has the potential to be developed as new kind of antimicrobial agents with novel action mechanism. However, the susceptibility to protease is a drawback for potential peptides to be clini...
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Article
Cadmium re-distribution from pod and root zones and accumulation by peanut (Arachis hypogaea L.)
Peanut (Arachis hypogaea L.) genotypes may differ greatly with regard to cadmium (Cd) accumulation, but the underlying mechanisms remain unclear. To determine the key factors that may contribute to Cd re-distribu...
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Article
Open AccessPoplar PdMYB221 is involved in the direct and indirect regulation of secondary wall biosynthesis during wood formation
Wood is formed by the successive addition of secondary xylem, which consists of cells with a conspicuously thickened secondary wall composed mainly of cellulose, xylan and lignin. Currently, few transcription ...
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Article
A new general form of conjugate gradient methods with guaranteed descent and strong global convergence properties
Although the study of global convergence of the Polak–Ribière–Polyak (PRP), Hestenes–Stiefel (HS) and Liu–Storey (LS) conjugate gradient methods has made great progress, the convergence of these algorithms for...
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Article
Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in PKD1 and PKD2. The products of these genes associate to form heteromeric complexes. Several models have been proposed to explain the ...
