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Article
Open AccessApplication of the research electronic data capture (REDCap) system in a low- and middle income country– experiences, lessons, and challenges
The challenges of reliably collecting, storing, organizing, and analyzing research data are critical in low- and middle-income countries (LMICs), particularly in Sub-Saharan Africa where several healthcare and...
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Article
Spark plasma sintering and decomposition of the Y3NbO7:Eu phase
The spark plasma sintering (SPS) of Eu3+-doped Y3NbO7 niobate phase was investigated to obtain dense ceramics. Although SPS allowed obtaining high-density ceramics, decomposition of the niobate phase occurred at ...
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Article
Free convection effects on a vertical cone with variable viscosity and thermal conductivity
The present paper deals with a flow of a viscous incompressible fluid along a heated vertical cone, with due allowance for variations of viscosity and thermal diffusivity with temperature. The fluid viscosity ...
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Article
Advances in molecular probe-based labeling tools and their application to multiscale multimodal correlated microscopies
The need to determine the precise subcellular distribution of specific proteins and macromolecular complexes in cells and tissues has been the major driving force behind the development of new molecular-geneti...
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Article
Racial/ethnic differences in self-reported and biologic measures of chronic stress in pregnancy
Racial differences in chronic maternal stress may contribute to disparities in pregnancy outcomes. The objective is to identify racial and ethnic differences in self-reported and biologic measures of stress be...
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Article
Open AccessDRP1 inhibition rescues retinal ganglion cells and their axons by preserving mitochondrial integrity in a mouse model of glaucoma
Glaucoma is the leading cause of irreversible blindness and is characterized by slow and progressive degeneration of the optic nerve head axons and retinal ganglion cell (RGC), leading to loss of visual functi...
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Article
Uncovering an anthropogenic sea-level rise signal in the Pacific Ocean
Internal variability in the climate system makes it difficult to determine the rate of regional sea-level rise. This study uses satellite altimetry data and corrects for natural variability to determine the an...
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Article
Open AccessInhibition of cyclophilin D by cyclosporin A promotes retinal ganglion cell survival by preventing mitochondrial alteration in ischemic injury
Cyclosporin A (CsA) inhibits the opening of the mitochondrial permeability transition pore (MPTP) by interacting with cyclophilin D (CypD) and ameliorates neuronal cell death in the central nervous system agai...
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Article
Terahertz-driven harmonics
Researchers have demonstrated high-harmonic generation using strong terahertz pulses in a bulk solid without damaging it. The mechanism underpinning such an extreme nonlinearity also generates coherent electro...
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Article
A multifunctional protein EWS regulates the expression of Drosha and microRNAs
EWS (Ewing’s Sarcoma) gene encodes an RNA/DNA-binding protein that is ubiquitously expressed and involved in various cellular processes. EWS deficiency leads to impaired development and early senescence through u...
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Article
Open AccessInhibition of oxidative stress by coenzyme Q10 increases mitochondrial mass and improves bioenergetic function in optic nerve head astrocytes
Oxidative stress contributes to dysfunction of glial cells in the optic nerve head (ONH). However, the biological basis of the precise functional role of mitochondria in this dysfunction is not fully understoo...
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Article
Differential lineage specification of thymic epithelial cells from bipotent precursors revealed by TSCOT promoter activities
Mechanism of thymic compartmentalization was studied in the transgenic system using the promoter of thymic stromal cotransporter (TSCOT), a cortical thymic epithelium-specific gene. The transgenic 3.1 kb TSCOT...
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Article
Recovery from Parkinsonism with N-acetylcysteine-differentiated neurons
The upregulation of dopaminergic neuronal differentiation is necessary for stem cell therapy in Parkinson’s disease (PD). In this study, neuronal differentiation efficiency increased by more than 2 times in P1...
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Article
Influence of phytohormones on morphology and chlorophyll a fluorescence parameters in embryos of Fucus vesiculosus L. (Phaeophyceae)
While a variety of plant hormones from brown algae were described, there were few studies that examined the combined effects of these hormones on morphogenesis and photosynthetic physiology in develo** fucoi...
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Chapter and Conference Paper
Porosity and Pore-Size Distribution of Geomaterials from X-ray CT Scans
Determination of transport properties of geomaterials is an important issue in many fields of engineering analysis and design. For example, in petroleum engineering, permeability of an oil reservoir may be cru...
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Article
Experimental studies on the heating performance of the PTC heater and heat pump combined system in fuel cells and electric vehicles
In this study, a combined system consisting of a heat pump and a PTC heater was developed as a heating unit in electric vehicles. The system consists of a compressor, a condenser, an evaporator, an expansion d...
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Article
N-acetylcysteine enhances neuronal differentiation of P19 embryonic stem cells via Akt and N-cadherin activation
We examined whether N-acetylcysteine (NAC) enhanced embryonic body (EB) formation and neuronal differentiation in terms of EB formation, neuronal marker (microtubule-associated protein 2; MAP-2) expression, and n...
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Article
ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease
Aberrant chromatin remodeling is involved in the pathogenesis of Huntington's disease (HD) but the mechanism is not known. Herein, we report that mutant huntingtin (mtHtt) induces the transcription of alpha th...
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Article
Influence of magnetic field and thermal radiation by natural convection past vertical cone subjected to variable surface heat flux
A numerical study is performed to examine the heat transfer characteristics of natural convection past a vertical cone under the combined effects of magnetic field and thermal radiation. The surface of the con...
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Article
Open AccessA new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics
Glutamate excitotoxicity leads to fragmented mitochondria in neurodegenerative diseases, mediated by nitric oxide and S-nitrosylation of dynamin-related protein 1, a mitochondrial outer membrane fission protein.
