7 Result(s)

Article

CR6-interacting factor 1 is a key regulator in Aβ-induced mitochondrial disruption and pathogenesis of Alzheimer’s disease

Mitochondrial dysfunction, often characterized by massive fission and other morphological abnormalities, is a well-known risk factor for Alzheimer’s disease (AD). One causative mechanism underlying AD-associat...

J Byun, S M Son, M-Y Cha, M Shong, Y J Hwang, Y Kim, H Ryu… in Cell Death & Differentiation (2015)

Article

Erratum to: Percutaneous insertion of Zilver stent in malignant biliary obstruction

Y. H. Han, M.-Y. Kim, S. Y. Kim, Y. H. Kim, Y. J. Hwang, J. W. Seo… in Abdominal Imaging (2014)

Article

A multifunctional protein EWS regulates the expression of Drosha and microRNAs

EWS (Ewing’s Sarcoma) gene encodes an RNA/DNA-binding protein that is ubiquitously expressed and involved in various cellular processes. EWS deficiency leads to impaired development and early senescence through u...

K Y Kim, Y J Hwang, M-K Jung, J Choe, Y Kim, S Kim, C-J Lee… in Cell Death & Differentiation (2014)

Article

ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease

Aberrant chromatin remodeling is involved in the pathogenesis of Huntington's disease (HD) but the mechanism is not known. Herein, we report that mutant huntingtin (mtHtt) induces the transcription of alpha th...

J Lee, Y K Hong, G S Jeon, Y J Hwang, K Y Kim, K H Seong… in Cell Death & Differentiation (2012)

Article

Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease

Huntington's disease (HD) is an autosomal-dominant neurological disorder caused by expanded CAG repeats in the Huntingtin (Htt) gene, but it is not known how this mutation causes neurodegeneration. Herein, we fou...

J Lee, Y J Hwang, J H Boo, D Han, O K Kwon, K Todorova… in Cell Death & Differentiation (2011)