-
Article
Open AccessThe curative effects of the traditional Chinese herbal medicine “**chuang ointment” on excisional wounds
“**chuang ointment” is a traditional Chinese herbal medicine for external incised wounds. This herbal medicine has been successfully used to treat patients with diabetic foot ulcers and pressure sores in Taiw...
-
Article
Open AccessHydrogen peroxide inducible clone-5 sustains NADPH oxidase-dependent reactive oxygen species-c-jun N-terminal kinase signaling in hepatocellular carcinoma
Target therapy aiming at critical molecules within the metastatic signal pathways is essential for prevention of hepatocellular carcinoma (HCC) progression. Hic-5 (hydrogen peroxide inducible clone-5) which be...
-
Article
Open AccessThe benefit of secondary prevention with oat fiber in reducing future cardiovascular event among CAD patients after coronary intervention
There is limited information about the association between oat fiber intake and future cardiovascular events in CAD patients after coronary intervention for secondary prevention. This study enrolled 716 patien...
-
Article
Reactive oxygen species-mediated PKC and integrin signaling promotes tumor progression of human hepatoma HepG2
The poor prognosis and recurrence of HCC are majorly caused by intrahepatic metastasis. Delineating the molecular pathways mediating these processes may benefit develo** effective targeting therapies. Using ...
-
Chapter
Overview of Signal Transduction in Tumor Metastasis
The signal transductions mediating each stage of tumor metastasis are gradually unraveled. A lot of growth factors and cytokines secreted in the tumor environment may trigger epithelial–mesenchymal transition ...
-
Chapter
The Role of ROS Signaling in Tumor Progression
Reactive oxygen species (ROS) are recently proposed to be involved in tumor metastasis which is a complicated processes including epithelial–mesenchymal transition (EMT), migration, invasion of the tumor cells...
-
Chapter
Signal Cross Talks for Sustained MAPK Activation and Cell Migration Mediated by Reactive Oxygen Species: The Involvement in Tumor Progression
Signal transduction exerted by the microenvironment around the primary tumor locus may trigger tumor metastasis especially at the migration stage. Sustained mitogen activated protein kinase (MAPK) signaling in...
-
Article
Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species
Signal transduction exerted by the microenvironment around the primary tumor locus may trigger tumor metastasis especially at the migration stage. Sustained mitogen activated protein kinase (MAPK) signaling in...
-
Article
The transcriptional factor Snail simultaneously triggers cell cycle arrest and migration of human hepatoma HepG2
Snail was recently highlighted as a critical transcriptional factor for tumor metastasis. Real time RT/PCR and Western blot analysis demonstrated that Snail mRNA and protein, respectively, were induced by 12-O-te...
