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    Article

    Reactive oxygen species-mediated PKC and integrin signaling promotes tumor progression of human hepatoma HepG2

    The poor prognosis and recurrence of HCC are majorly caused by intrahepatic metastasis. Delineating the molecular pathways mediating these processes may benefit develo** effective targeting therapies. Using ...

    Chi-Tan Hu, Jia-Ru Wu, Chuan-Chu Cheng, Sindy Wang in Clinical & Experimental Metastasis (2011)

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    The transcriptional factor Snail simultaneously triggers cell cycle arrest and migration of human hepatoma HepG2

    Snail was recently highlighted as a critical transcriptional factor for tumor metastasis. Real time RT/PCR and Western blot analysis demonstrated that Snail mRNA and protein, respectively, were induced by 12-O-te...

    Chi-Tan Hu, Jia-Ru Wu, Tsu Yao Chang, Chuan-Chu Cheng in Journal of Biomedical Science (2008)