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Article
Reactive oxygen species-mediated PKC and integrin signaling promotes tumor progression of human hepatoma HepG2
The poor prognosis and recurrence of HCC are majorly caused by intrahepatic metastasis. Delineating the molecular pathways mediating these processes may benefit develo** effective targeting therapies. Using ...
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Article
The transcriptional factor Snail simultaneously triggers cell cycle arrest and migration of human hepatoma HepG2
Snail was recently highlighted as a critical transcriptional factor for tumor metastasis. Real time RT/PCR and Western blot analysis demonstrated that Snail mRNA and protein, respectively, were induced by 12-O-te...