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  1. Article

    Open Access

    Novel therapeutic activities of dragon blood from palm tree Daemonorops draco for the treatment of chronic diabetic wounds

    The clinical efficacy of **chuang Ointment, a traditional Chinese medicine (TCM), in treating chronic non-healing diabetic wounds has been demonstrated over the past decades. Both in vitro and in vivo angioge...

    Hong-Chi Chen, Ren-In You, Fang-Mei Lin, Guan-Ling Lin, Tsung-Jung Ho in Botanical Studies (2024)

  2. Article

    Open Access

    A cohort study: The Association Between Autoimmune Disorders and Leptospirosis

    There are limited studies on the association between systemic autoimmune rheumatic diseases (SARDs) and leptospirosis. Therefore, this study aims to identify the effects of leptospirosis on the risks of develo...

    Soon-Hian Teh, Ren-In You, Yu-Cih Yang, Chung Y. Hsu in Scientific Reports (2020)

  3. Article

    Open Access

    Hydrogen peroxide inducible clone-5 sustains NADPH oxidase-dependent reactive oxygen species-c-jun N-terminal kinase signaling in hepatocellular carcinoma

    Target therapy aiming at critical molecules within the metastatic signal pathways is essential for prevention of hepatocellular carcinoma (HCC) progression. Hic-5 (hydrogen peroxide inducible clone-5) which be...

    Jia-Ru Wu, Ren-In You, Chi-Tan Hu, Chuan-Chu Cheng, Rudy Rudy, Wen-Sheng Wu in Oncogenesis (2019)

  4. Article

    Open Access

    Author Correction: Snail collaborates with EGR-1 and SP-1 to directly activate transcription of MMP 9 and ZEB1

    A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.

    Wen-Sheng Wu, Ren-In You, Chuan-Chu Cheng, Ming-Che Lee, Teng-Yi Lin in Scientific Reports (2018)

  5. Article

    Open Access

    Functional characterization of chitin-binding lectin from Solanum integrifolium containing anti-fungal and insecticidal activities

    Along with the rapid development of glycomic tools, the study of lectin–carbohydrate interactions has expanded, opening the way for applications in the fields of analytic, diagnostic, and drug delivery. Chitin...

    Chang-Shan Chen, Chun-Yi Chen, Divya Malathy Ravinath in BMC Plant Biology (2018)

  6. Article

    Open Access

    Snail collaborates with EGR-1 and SP-1 to directly activate transcription of MMP 9 and ZEB1

    The Snail transcription factor plays as a master regulator of epithelial mesenchymal transition (EMT), one of the steps of tumor metastasis. Snail enhances expressions of a lot of mesenchymal genes including t...

    Wen-Sheng Wu, Ren-In You, Chuan-Chu Cheng, Ming-Che Lee, Teng-Yi Lin in Scientific Reports (2017)

  7. No Access

    Article

    SHP-1 (PTPN6) keeps the inflammation at bay: limiting IL-1α-mediated neutrophilic dermatoses by preventing Syk kinase activation

    Ren-In You, Ching-Liang Chu in Cellular & Molecular Immunology (2017)

  8. Article

    Open Access

    Highly potent antimicrobial modified peptides derived from the Acinetobacter baumannii phage endolysin LysAB2

    The increase in the prevalence of multidrug-resistant Acinetobacter baumannii (MDRAB) strains is a serious public health concern. Antimicrobial peptides (AMPs) are a possible solution to this problem. In this stu...

    Shih-Yi Peng, Ren-In You, Meng-Jiun Lai, Nien-Tsung Lin in Scientific Reports (2017)

  9. Article

    Open Access

    miRNome traits analysis on endothelial lineage cells discloses biomarker potential circulating microRNAs which affect progenitor activities

    Endothelial progenitor cells (EPCs) play a fundamental role in not only blood vessel development but also post-natal vascular repair. Currently EPCs are defined as early and late EPCs based on their biological...

    Ting-Yu Chang, Tse-Shun Huang, Hsei-Wei Wang, Shing-Jyh Chang, Hung-Hao Lo in BMC Genomics (2014)