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Article
Cricopharyngeal muscle origin transection for oropharyngeal dysphagia, a novel surgical technique
Cricopharyngeal myotomy improves pharyngeal dysphagia by resecting the cricopharyngeal muscle.
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Article
Open AccessCough-Inducing Method Using a Tartaric Acid Nebulizer for Patients with Silent Aspiration
The tartaric acid nebulizer is a well-known cough test to evaluate cough function. This study aimed to evaluate the effectiveness of a cough-inducing method using tartaric acid (CiTA). Patients with dysphagia ...
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Chapter
Clinical Application of iPSC-Derived Cardiomyocytes in Patients with Advanced Heart Failure
Restoration of damaged cardiac tissues via supplementation with functional cardiomyocytes is an ideal medical treatment for advanced heart failure. Because human induced pluripotent stem cells (hiPSCs) can the...
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Article
Appropriate device selection for transcatheter atrial septal defect closure using three-dimensional transesophageal echocardiography
Detail morphological evaluation for ASD is essential to achieve successful transcatheter closure. Three-dimensional transesophageal echocardiography (3D-TEE) is emerging, but few studies have comprehensively v...
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Article
Open AccessCryoinjury-induced acute myocardial infarction model and ameroid constrictor-induced ischemic heart disease model in adult micro-mini pigs for preclinical studies
Coronary artery diseases (CAD) are the most commonly occurring disorders in the developed countries. Development of new therapeutics and their success in clinical studies require confirmation of therapeutic ef...
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Chapter
Road to Heart Regeneration with Induced Pluripotent Stem Cells
Restoration of cardiac function is the most desirable treatment of severe heart failure. However, effective regenerative therapy for the lost cardiomyocytes is currently an unmet medical need. Induced pluripot...
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Article
Prognostic implications of optimal medical therapy in patients undergoing percutaneous coronary intervention for acute coronary syndrome in octogenarians
The proportion of elderly acute coronary syndrome (ACS) patients who receive optimal medical therapy (OMT) after percutaneous coronary intervention (PCI) and whether OMT affects their long-term outcomes remain...
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Article
Intracardiac echocardiography for percutaneous closure of atrial septal defects: initial experiences in Japan
Transcatheter closure of secundum atrial septal defect (ASD) has been widely performed as a less invasive alternative to surgery with zero mortality so far in Japan. In the US and Europe, intracardiac echocard...
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Article
Sema3a maintains normal heart rhythm through sympathetic innervation patterning
Sympathetic innervation is critical for effective cardiac function. However, the developmental and regulatory mechanisms determining the density and patterning of cardiac sympathetic innervation remain unclear...