Skip to main content

8 Result(s)

within Atsushi Anzai Remove this filter

and

  1. Article

    Open Access

    Omega-3 fatty acid epoxides produced by PAF-AH2 in mast cells regulate pulmonary vascular remodeling

    Pulmonary hypertension is a fatal rare disease that causes right heart failure by elevated pulmonary arterial resistance. There is an unmet medical need for the development of therapeutics focusing on the pulm...

    Hidenori Moriyama, ** Endo, Masaharu Kataoka, Yuta Shimanaka… in Nature Communications (2022)

    Download PDF (3032 KB) View Article

  2. No Access

    Article

    Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease

    Communication within the glial cell ecosystem is essential for neuronal and brain health1–3. The influence of glial cells on the accumulation and clearance of β-amyloid (Aβ) and neurofibrillary tau in the brains ...

    Cameron S. McAlpine, Joseph Park, Ana Griciuc, Eunhee Kim, Se Hoon Choi… in Nature (2021)

  3. No Access

    Article

    Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease

    The biochemical response to food intake must be precisely regulated. Because ingested sugars and fats can feed into many anabolic and catabolic pathways1, how our bodies handle nutrients depends on strategically ...

    Shun He, Florian Kahles, Sara Rattik, Manfred Nairz, Cameron S. McAlpine… in Nature (2019)

  4. No Access

    Article

    Sleep modulates haematopoiesis and protects against atherosclerosis

    Sleep is integral to life1. Although insufficient or disrupted sleep increases the risk of multiple pathological conditions, including cardiovascular disease2, we know little about the cellular and molecular mech...

    Cameron S. McAlpine, Máté G. Kiss, Sara Rattik, Shun He, Anne Vassalli… in Nature (2019)

  5. No Access

    Article

    On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

    Damaged erythrocytes accumulate in various pathological conditions, such as hemolytic anemia, anemia of inflammation, and sickle cell disease. In mice challenged with damaged erythorcytes, a monocyte subset mi...

    Igor Theurl, Ingo Hilgendorf, Manfred Nairz, Piotr Tymoszuk… in Nature Medicine (2016)

  6. No Access

    Article

    Prognostic implications of optimal medical therapy in patients undergoing percutaneous coronary intervention for acute coronary syndrome in octogenarians

    The proportion of elderly acute coronary syndrome (ACS) patients who receive optimal medical therapy (OMT) after percutaneous coronary intervention (PCI) and whether OMT affects their long-term outcomes remain...

    Atsushi Anzai, Yuichiro Maekawa, Masaki Kodaira, Satoshi Mogi… in Heart and Vessels (2015)

  7. No Access

    Article

    Intracardiac echocardiography for percutaneous closure of atrial septal defects: initial experiences in Japan

    Transcatheter closure of secundum atrial septal defect (ASD) has been widely performed as a less invasive alternative to surgery with zero mortality so far in Japan. In the US and Europe, intracardiac echocard...

    Sayaka Shimizu, Akio Kawamura, Takahide Arai… in Cardiovascular Intervention and Therapeuti… (2013)

  8. No Access

    Article

    Eicosapentaenoic acid suppresses adverse effects of C-reactive protein overexpression on pressure overload-induced cardiac remodeling

    Serum C-reactive protein (CRP) elevation is associated with poor clinical outcome in patients with heart failure (HF). We previously reported that CRP exacerbates the development of pressure overload-induced c...

    Toshiyuki Nagai, Toshihisa Anzai, Yoshinori Mano, Hidehiro Kaneko… in Heart and Vessels (2013)