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Article
Status of the crystallography beamlines at Elettra
Elettra is one of the first 3rd-generation storage rings, recently upgraded to routinely operate in top-up mode at both 2.0 and 2.4 GeV. The facility hosts four dedicated beamlines for crystallography, two ope...
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Article
Long-term results of the Italian Association of Pediatric Hematology and Oncology (AIEOP) Acute Lymphoblastic Leukemia Studies, 1982–1995
The first multicentric approach to childhood acute lymphoblastic leukemia (ALL) treatment in Italy started in the early 1970s when the Associazione Italiana di Ematologia ed Oncologia Pediatrica (AIEOP) was fo...
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Article
Low serum inhibin B levels as a marker of testicular damage after treatment for a childhood malignancy
The aim of this study was to evaluate the role of inhibin B and the determination of its concentration to diagnose testicular damage after treatment for a childhood malignancy. Thirty-seven males treated for ...
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Article
Immunotherapy with low-dose recombinant interleukin 2 after high-dose chemotherapy and autologous stem cell transplantation in neuroblastoma
The purpose of this study was to evaluate in a phase I-II trial whether low doses of recombinant human interleukin 2 (rHuIL-2) over a prolonged period of time are safe and effective in eradicating or controlli...
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Article
Abnormal insulin response to glucose following treatment for Wilms' tumor in childhood
To determine whether β-cell function could be impaired by the treatment for Wilms' tumour (WT) in childhood, we investigated the insulin secretion of 44 survivors of WT (22 males) with a median off-treatment ...
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Article
Prognostic relevance of pretreatment proliferative rapidity of marrow blast cells in childhood acute lymphoblastic leukaemia
Cell proliferation rate is a well-established prognostic factor in cancer, but it has not been considered to identify the risk group of childhood acute lymphoblastic leukaemia (ALL) at presentation. We carried...
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Article
Longitudinal growth and final height in long-term survivors of childhood leukaemia
Survival of children with acute lymphoblastic leukaemia (ALL) has increased considerably in recent years and data on the spontaneous growth and final height of these children are conflicting. Therefore, we ana...
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Chapter and Conference Paper
Therapy of Childhood Acute Myelogenous Leukemia: An Update of the AIEOP/LAM 8204 Study
Over the past decade there have been significant advances in the treatment of acute myelogenous leukemia (AML). The introduction of intensive induction and post-remission chemotherapy programs, together with t...
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Chapter and Conference Paper
Neoadjuvant Chemotherapy for Osteosarcoma
From March 1983 to September 1986, 126 patients with localized high-grade osteosarcoma of the extremities were treated with neoadjuvant chemotherapy. Preoperative treatment consisted of two cycles of i.v. meth...
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Chapter
Neoadjuvant Chemotherapy for Osteosarcoma — Results of a Prospective Study
In March 1983, the Bone Tumor Center of the Istituto Ortopedico Rizzoli of Bologna, in collaboration with the Department of Pediatric Oncology of the University of Torino, and the 3rd Pediatric Clinic of the U...
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Chapter and Conference Paper
Occurrence of T-Cell Features in a Child’s Lymphoproliferative Disorder
T cell chronic lymphocytic leukemia (T-CLL) is a lymphoproliferative disorder which has never before been observed in patients younger than 20 years. Therefore, the occurrence of a lymphoproliferative disorder...
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Chapter and Conference Paper
Transitional Pre-B to B Acute Lymphoblastic Leukemia
Approximately 20% of patients with acute lymphoblastic leukemia (ALL) present features of pre-B cells, i. e., small quantities of p, heavy chains in their cytoplasm and no detectable surface immunoglobulin [1,...
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Chapter
Adverse Sequelae of Central Nervous System Prophylaxis in Acute Lymphoblastic Leukemia
Using currently available optimal therapy, approximately 50% of patients with Acute Lymphoblastic Leukemia (ALL) will be disease-free 5 years after diagnosis. Critical to successful therapy is the prevention o...
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Article
Preparation and crystal structure of bis(protonated 2,6-diacetylpyridine bis(phenylhydrazone)) uranyl tetrachloride, CH3CN
The reaction of 2,6-diacetylpyridine-bis(phenylhydrazone),L, with commercial uranyl chloride under a variety of different conditions gave only complexes of the type [2LH]2+[UO2Cl4]2−,xCH3CN (x = 1 or 2). The stru...