55 Result(s)

Article

NUP98-fusion transcripts characterize different biological entities within acute myeloid leukemia: a report from the AIEOP-AML group

V Bisio, M Zampini, C Tregnago, E Manara, V Salsi, A Di Meglio, R Masetti… in Leukemia (2017)

Article

Usefulness of liver stiffness measurement in predicting hepatic veno-occlusive disease development in patients who undergo HSCT

A Colecchia, G Marasco, F Ravaioli, K Kleinschmidt… in Bone Marrow Transplantation (2017)

Article

Gut microbiota and hematopoietic stem cell transplantation: where do we stand?

Advances in biological techniques have potentiated great progresses in understanding the interaction between human beings and the ∼10 to 100 trillion microbes living in their gastrointestinal tract: gut microb...

D Zama, E Biagi, R Masetti, P Gasperini, A Prete, M Candela… in Bone Marrow Transplantation (2017)

Article

Characterization of children with FLT3-ITD acute myeloid leukemia: a report from the AIEOP AML-2002 study group

Recurrent molecular markers have been routinely used in acute myeloid leukemia (AML) for risk assessment at diagnosis, whereas their post-induction monitoring still represents a debated issue. We evaluated the...

E Manara, G Basso, M Zampini, B Buldini, C Tregnago, R Rondelli, R Masetti… in Leukemia (2017)

Article

Gut microbiota trajectory in pediatric patients undergoing hematopoietic SCT

Acute GvHD (aGvHD) is the main complication of hematopoietic SCT (HSCT) during the treatment of hematological disorders. We carried out the first longitudinal study to follow the gut microbiota trajectory, fro...

E Biagi, D Zama, C Nastasi, C Consolandi, J Fiori… in Bone Marrow Transplantation (2015)

Article

Relationships between thyroid function and autoimmunity with metabolic derangement at the onset of type 1 diabetes: a cross-sectional and longitudinal study

Type 1 diabetes (T1DM) is an autoimmune disease often associated with thyroid abnormalities.

C. Balsamo, S. Zucchini, G. Maltoni, A. Rollo… in Journal of Endocrinological Investigation (2015)

Article

Outcome of children with high-risk acute myeloid leukemia given autologous or allogeneic hematopoietic cell transplantation in the aieop AML-2002/01 study.

We analyzed the outcome of 243 children with high-risk (HR) AML in first CR1 enrolled in the AIEOP-2002/01 protocol, who were given either allogeneic (ALLO; n=141) or autologous (AUTO; n=102) hematopoietic SCT (H...

F Locatelli, R Masetti, R Rondelli, M Zecca, F Fagioli… in Bone Marrow Transplantation (2015)

Article

Risk factor analysis of posterior reversible encephalopathy syndrome after allogeneic hematopoietic SCT in children

D Zama, R Masetti, D M Cordelli, F Vendemini, L Giordano… in Bone Marrow Transplantation (2014)

Article

Juvenile arthritis after haematopoietic stem cell transplantation

E Tronconi, A Miniaci, A Prete, R Masetti, A Pession in Bone Marrow Transplantation (2014)

Article

Activity of the pan-class I phosphoinositide 3-kinase inhibitor NVP-BKM120 in T-cell acute lymphoblastic leukemia

Constitutively active phosphoinositide 3-kinase (PI3K) signaling is a common feature of T-cell acute lymphoblastic leukemia (T-ALL), where it upregulates cell proliferation, survival and drug resistance. These...

A Lonetti, I L Antunes, F Chiarini, E Orsini, F Buontempo, F Ricci, P L Tazzari… in Leukemia (2014)

Article

Cytotoxic activity of the casein kinase 2 inhibitor CX-4945 against T-cell acute lymphoblastic leukemia: targeting the unfolded protein response signaling

Constitutively active casein kinase 2 (CK2) signaling is a common feature of T-cell acute lymphoblastic leukemia (T-ALL). CK2 phosphorylates PTEN (phosphatase and tensin homolog) tumor suppressor, resulting in...

F Buontempo, E Orsini, L R Martins, I Antunes, A Lonetti, F Chiarini… in Leukemia (2014)

Article

Detection of PICALM-MLLT10 (CALM-AF10) and outcome in children with T-lineage acute lymphoblastic leukemia

L Lo Nigro, E Mirabile, M Tumino, C Caserta, G Cazzaniga, C Rizzari… in Leukemia (2013)

Article

Brachial amyotrophic diplegia associated with the a140a superoxide dismutase 1 mutation

L. Di Vito, D. de Biase, A. Pession, M. Visani, R. Liguori… in neurogenetics (2013)

Article

Severe hypoglycemic episodes: A persistent threat for children with Type 1 diabetes mellitus and their families

Background: As lowering glycated hemoglobin (HbA_1c) levels is still the main goal of insulin treatment, severe hypoglycemia (SH) remains a common experience in children with Type 1 diabetes melli...

G. Maltoni MD, S. Zucchini, M. Scipione… in Journal of Endocrinological Investigation (2013)

Article

Cytotoxic activity of the novel Akt inhibitor, MK-2206, in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive neoplastic disorder arising from T-cell progenitors. T-ALL accounts for 15% of newly diagnosed ALL cases in children and 25% in adults. Although the...

C Simioni, L M Neri, G Tabellini, F Ricci, D Bressanin, F Chiarini… in Leukemia (2012)

Article

AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications

The mammalian target of rapamycin (mTOR) serine/threonine kinase is the catalytic subunit of two multi-protein complexes, referred to as mTORC1 and mTORC2. Signaling downstream of mTORC1 has a critical role in...

C Grimaldi, F Chiarini, G Tabellini, F Ricci, P L Tazzari, M Battistelli… in Leukemia (2012)

Article

Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles

Patients with Down syndrome (DS) and acute lymphoblastic leukemia (ALL) have distinct clinical and biological features. Whereas most DS-ALL cases lack the sentinel cytogenetic lesions that guide risk assignmen...

M G Loudin, J Wang, H-C Eastwood Leung, S Gurusiddappa, J Meyer, G Condos… in Leukemia (2011)

Article

Frequency and prognostic implications of JAK 1-3 aberrations in Down syndrome acute lymphoblastic and myeloid leukemia

M Blink, T D Buitenkamp, M M van den Heuvel-Eibrink, A A Danen-van Oorschot… in Leukemia (2011)