-
Article
Short-term effects of growth hormone treatment on the upper airways of non severely obese children with Prader-Willi syndrome
Aims: The aim of this study was to establish whether short-term GH treatment causes obstructive apnea in patients with Prader-Willi syndrome and normal upper airway patency. Subjects and ...
-
Chapter
Effects of IL-2 Immunomodulation on Infectious Complications in Colorectal Surgery
Immunosuppression and starvation are the most important risk factors for sepsis after major abdominal surgery; both of them are present in advanced cancer disease, and infective complications are frequent in s...
-
Article
Down syndrome: 130 years after its identification
-
Article
The impact of paediatric bone marrow transplantation on quality of life
-
Article
Sinus histiocytosis with massive lymphoadenopathy (Rosai-Dorfman disease). Clinico-pathological analysis of a paediatric case
Histochemical and immunohistochemical studies performed in only a few cases of sinus histiocytosis with massive lymphoadenopathy (SHML) indicated that SHML cells belong to themacrophage — histiocyte system, th...
-
Chapter and Conference Paper
Therapy of Childhood Acute Myelogenous Leukemia: An Update of the AIEOP/LAM 8204 Study
Over the past decade there have been significant advances in the treatment of acute myelogenous leukemia (AML). The introduction of intensive induction and post-remission chemotherapy programs, together with t...
-
Article
A notation on individuality, 50 years after the death of Sigmund Freud. Toward a “biological Ego”?
-
Article
Juvenile chronic myeloid leukaemia and alpha-interferon
-
Article
Cell-mediated cytotoxicity in down syndrome: impairment of allogeneic mixed lymphocyte reaction, NK and NK-like activities
Peripheral blood mononuclear cells (PBMC) from 16 non-institutionalized patients with Down syndrome (DS) were studied with various monoclonal antibodies and analysed for natural killer (NK), and NK-like activi...
-
Article
VMA-negative, MIBG scan-positive neuroblastoma in children
-
Article
Familial haemophagocytic lymphohistiocytosis in two brothers: Possible relationship between impaired immune function and clinical picture of graft-versus-host disease
-
Chapter and Conference Paper
Ascaris Suum Extract: Polyclonal Activator Properties as Possible Tools for Investigating in Vitro IgE Production in Humans
Intestinal infestation by parasites such as Nypponstrongylus brasiliensis and Ascaris suum is usually associated with high levels of serum IgE in animals and humans [1, 2].
-
Article
Selective IgA deficiency: Clinical and immunological evaluation of 50 pediatric patients
Fifty children with IgA deficiency were followed for 1 to 4 years from 1975 to 1978. Thirty-five had complete deficiency of serum IgA (<2.5 IU/ml) and 15 partial deficiency (serum IgA below the 10th centile fo...
-
Article
A rapid unfavorable outcome of wegener's granulomatosis in early childhood
Wegener's Granulomatosis was suspected in a 27-month-old female with a nodular, necrotizing lesion of the nose, diffuse subcutaneous nodules, and erythematous desquamation of the entire body. From 20 months of...
-
Article
36 INTERACTION OF LPS AND CONA IN HUMN LYMPHOCYTE ACTIVATION. II: EFFECT ON CELL PROLIFERATION
In order to evaluate the cellular basis of the synergistic effect of LPS and ConA on in vitro IgM production their effect on cell proliferation was studied under identical experimental conditions in normal sub...
-
Article
37 ConA-INDUCED THYMUS-DEPENDENT Ig PRODUCTION BY HUMAN B LYMPHOCYTES IN VITRO
While there is good evidence that PWM activates helper T cells for Ig production, the effect of ConA is usually that of suppression. T and B cells were separated from tonsils by E-rosetting and cultured in the...
-
Chapter and Conference Paper
A Mathematical Model of the “Two Signal” Theory for T-B Cells Cooperation
The immune system recognizes an extremely high number of antigenic molecules by means of receptors located on the surface of the lymphocytes, the immunocompetent cells.
-
Article
Atopy as a minimal immunodeficiency?
Despite impressive recent advances in the understanding of the chemical and cellular bases of the reaginic response, the pathogenesis of atopic diseases still remains a matter of speculation. The frequent find...
-
Article
HUMAN B CEIL DIFFERENTIATION IN VITRO. KINETICS TO THE RESPONSE TO POKEWEED MITOGEN (PWM)
Human peripheral blood lymphocytes (106/ml) from 5 healthy young adults were cultured for 10 days in serum-supplemented RPMI 1640 and stimulated with PWM. Data recording at daily intervals revealed the following ...
-
Article
Peripheral blood ‘Rosette forming lymphocytes’ in Down's syndrome
La reattività alla fitoemoagglutinina e la capacità di formare «rosette» con eritrociti di montone dei linfociti di sangue periferico è risultata significativamente depressa in soggetti adulti affetti da sindr...
