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    Article

    Molecular monitoring of the tumor load predicts progressive disease in patients with multiple myeloma after high-dose therapy with autologous peripheral blood stem cell transplantation

    The clinical relevance of the assessment of minimal residual disease (MRD) in patients with multiple myeloma (MM) to predict disease recurrence has not been proven. In the present study, we retrospectively ana...

    E Lipinski, FW Cremer, AD Ho, H Goldschmidt, M Moos in Bone Marrow Transplantation (2001)

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    Article

    Evaluation of the kinetics of the bone marrow tumor load in the course of sequential high-dose therapy assessed by quantitative PCR as a predictive parameter in patients with multiple myeloma

    The aim of this investigation was to examine the possible clinical significance of the kinetics of bone marrow (BM) tumor load during the course of sequential high-dose therapy (HDT) as assessed by quantitativ...

    FW Cremer, E Ehrbrecht, K Kiel, A Benner, U Hegenbart, AD Ho in Bone Marrow Transplantation (2000)

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    Article

    CD19+ and CD20+ B cells from the peripheral blood of patients with multiple myeloma are not infected with human herpesvirus 8

    T Bösing, F Bellos, FW Cremer, C Gemmel, G Moldenhauer, AD Ho, H Goldschmidt in Leukemia (2000)

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    Article

    Analysis of circulating tumor cells in patients with multiple myeloma during the course of high-dose therapy with peripheral blood stem cell transplantation

    In multiple myeloma (MM) circulating CD19+ cells have been considered as myeloma precursors. As these cells are also possibly a reservoir of treatment resistant disease evaluation of the CD19+ cells during the co...

    K Kiel, FW Cremer, C Rottenburger, C Kallmeyer, E Ehrbrecht in Bone Marrow Transplantation (1999)

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    Article

    First and second apheresis in patients with multiple myeloma: no differences in tumor load and hematopoietic stem cell yield

    Autologous peripheral blood stem cells (PBSC) are now widely used to support myeloablative therapy in patients with multiple myeloma (MM). The presence of malignant cells in these autografts has been demonstra...

    K Kiel, FW Cremer, E Ehrbrecht, M Wallmeier, U Hegenbart in Bone Marrow Transplantation (1998)