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Chapter
Factors predisposing cancer patients to infection
As a consequence of major advances in medicine in the last few decades, patients with illnesses previously considered untreatable may now receive appropriate treatment and survive. Unfortunately, this progress...
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Article
The desire to be fashionable. Should we consider it a risk factor for infection in adolescents with acute leukaemia?
Three cases of skin infection, two with Pseudomonas aeruginosa and one with Staphylococcus aureus in three adolescents with acute leukaemia are described. In all cases the infection was clearly related to the la...
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Article
Cotrimoxazole prophylaxis of Pneumocystis carinii infection during the treatment of childhood acute lymphoblastic leukemia – beware non compliance in older children and adolescents
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Article
The role of heparin prophylaxis and Doppler ultrasound examination in preventing and diagnosing central venous catheter related complications
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Article
A single institution observational study of early mechanical complications in central venous catheters (valved and open-ended) in children with cancer
The use of indwelling central venous catheters (CVCs) has become essential for managing children undergoing cancer treatment. Various types of CVCs are available, but reports on complications observed in pedia...
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Article
Urokinase for restoring patency of malfunctioning or blocked central venous catheters in children with hemato-oncological diseases
To evaluate differences in success rate between two dosages of intraluminal urokinase (IL-UK) for treatment of withdraw occlusion in central venous catheters (CVC) and to confirm the efficacy of a salvage prot...
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Article
Correlation between “malfunctioning events” and catheter-related infections in pediatric cancer patients bearing tunneled indwelling central venous catheter: results of a prospective observational study
To evaluate the possible link between malfunctioning events and catheter related infections in indwelling central venous devices in children with cancer.
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Article
Open AccessSafety and efficacy of a caspofungin-based combination therapy for treatment of proven or probable aspergillosis in pediatric hematological patients
Fungal infections are diagnosed increasingly often in patients affected by hematological diseases and their mortality has remained high. The recent development of new antifungal drugs gives the clinician the p...
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Article
Clostridium difficile-associated disease in children with solid tumors
The goal of this study was to describe the incidence of Clostridium difficile-associated disease (CDAD) in children with solid tumours.
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Article
Near-miss events are really missed! Reflections on incident reporting in a department of pediatric surgery
The aim of this study was to evaluate the frequency of surgical and organizational events that occurred in the whole Department of Paediatric Surgery at Gaslini Children’s Hospital through an incident-reportin...
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Chapter
Infectious Complications of Antineoplastic Chemotherapy in Children with Acute Leukemia or Solid Tumors
Infections represent important complications during chemotherapy for pediatric malignancies. The incidence of infections varies according to the type of underlying disease, being higher in children with acute ...
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Article
Quantification of micafungin in human plasma by liquid chromatography-tandem mass spectrometry
Micafungin (MCF) is an antifungal agent of the echinocandin class approved in Europe both in adults and in children for the treatment of invasive candidiasis. Few analytical methods for therapeutic drug monito...
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Article
Erratum to: Quantification of micafungin in human plasma by liquid chromatography-tandem mass spectrometry
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Article
Open AccessMicafungin for the treatment of proven and suspected invasive candidiasis in children and adults: findings from a multicenter prospective observational study
A multicenter observational study was conducted in Italy to assess the safety of micafungin in the daily clinical practice for the treatment of proven and suspected invasive candidiasis (IC), as well as to des...
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Article
Open AccessPredicting microbiologically defined infection in febrile neutropenic episodes in children: global individual participant data multivariable meta-analysis
Risk-stratified management of fever with neutropenia (FN), allows intensive management of high-risk cases and early discharge of low-risk cases. No single, internationally validated, prediction model of the ri...
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Article
Erratum: Predicting microbiologically defined infection in febrile neutropenic episodes in children: global individual participant data multivariable meta-analysis
Correction to: British Journal of Cancer (2016) 114, 623–630. doi:10.1038/bjc.2016.28; published online 8 March 2016 Upon publication of the above paper in the British Journal of Cancer, the authors identified...
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Article
Resistance to oral antibiotics in 4569 Gram-negative rods isolated from urinary tract infection in children
To investigate antibiotic resistance among pathogens isolated from urines in a tertiary care children’s hospital in Italy. Retrospective analysis of prospectively collected data on antibiotic susceptibility of...
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Article
Fungal infections of the lung in children
Fungal infections of the lungs are relatively common and potentially life-threatening conditions in immunocompromised children. The role of imaging in children with lung mycosis is to delineate the extension o...
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Article
Open AccessProceedings of the 23rd Paediatric Rheumatology European Society Congress: part two
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Article
Management of Lyme Disease in European Children: a Review for Practical Purpose
Lyme disease is a tick-borne zoonosis transmitted through a bite of a tick carrying a spirochete belonging to Borrelia species. In the last 20 years, the reported incidence of Lyme disease is increased by three t...