-
Article
Concepts and perspectives on peptide-based immunotherapy in allergy
Allergen-specific T cells play a key role in the pathogenesis of allergic diseases through provision of help for allergen-specific B cells and control of inflammatory responses. Allergen immunotherapy using in...
-
Article
Concepts and perspectives on peptide-based immunotherapy in allergy
Allergen-specific T cells play a key role in the pathogenesis of allergic diseases through provision of help for allergen-specific B cells and control of inflammatory responses. Allergen immunotherapy using in...
-
Article
Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus
Microorganisms that breach the body's external defences and enter the lymphatic system are liable to be captured by the lymph nodes, and recent work showed that a subset of macrophages found in the subcapsular...
-
Protocol
B Cell Helper Assays
Activation, proliferation and differentiation of naïve B lymphocytes into memory B cells and plasma cells requires engagement of the B cell receptor (BCR) coupled to T-cell help (1, 2). T cells deliver help in co...