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Article
Cytotoxic therapy with etoposide and cisplatin in advanced adrenocortical carcinoma
Adrenocortical carcinoma (ACC) is a rare tumour with a poor prognosis. Cisplatin is the most widely tested cytotoxic agent in this disease. A total of 18 patients with advanced ACC were enrolled. Cytotoxic the...
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Article
Neuron-specific enolase and chromogranin A as markers of neuroendocrine tumours
Circulating neuron-specific enolase (NSE) and chromogranin A (CgA) were measured in 128 patients with neuroendocrine tumours (NET) to compare their sensitivity and specificity, to investigate factors associate...
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Article
Open AccessTreatment of poorly differentiated neuroendocrine tumours with etoposide and cisplatin
The purpose of this study was to evaluate by a retrospective analysis of 53 patients the efficacy of chemotherapy combining etoposide and cisplatin in the treatment of neuroendocrine tumours. The regimen was a...
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Article
Open AccessTreatment of advanced medullary thyroid cancer with an alternating combination of doxorubicin-streptozocin and 5 FU-dacarbazine
Combinations of doxorubicin and streptozocin and 5-FU and dacarbazine were given alternately to 20 patients with metastatic medullary thyroid carcinoma. Three partial responses and 10 long-term stabilizations ...
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Article
Open AccessChromogranin A and the α-subunit of glycoprotein hormones in medullary thyroid carcinoma and phaeochromocytoma
Using specific immunoradiometric assays, we evaluated the clinical usefulness of chromogranin A and the α-subunit of glycoprotein hormones in neuroendocrine tumours of neuroectodermic origin. The serum α-subun...
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Article
Open AccessLong-term outcome of medullary thyroid carcinoma in patients with normal postoperative medical imaging
Imaging-detected relapses are observed in a significant proportion of patients with medullary thyroid carcinoma (MTC) with normal postoperative imaging studies. The aim of this study was to search for prognost...
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Article
Sodium iodide symporter expression and radioiodine distribution in extrathyroidal tissues
The functional role of the sodium iodide symporter (NIS) in extrathyroidal tissues was investigated by examining its mRNA and protein expression, together with the evidence of radioiodine (131I) uptake in 302 pat...
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Article
Intérêt de la mesure individualisée de la qualité de vie en oncologie: utilisation du SEIQoL chez des patients traités pour tumeur neuro-endocrine
Les mesures individualisées de qualité de vie en oncologie peuvent apporter des informations spécifiques et complémentaires à celles qui sont issues des mesures standardisées de qualité de vie. Cet article ill...
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Chapter
Tumeurs endocrines gastro-entéro-pancréatiques (TE GEP): facteurs pronostiques
Ce chapitre fait le point sur les facteurs pronostiques des tumeurs endocrines gastro-entéro-pancréatiques (TE GEP) non à petites cellules (1, 2). Nous utiliserons le terme de « tumeur endocrine », pour définir d...
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Chapter
Chimiothérapie des tumeurs endocrines
Le rôle des traitements médicaux dans la prise en charge des tumeurs endocrines digestives et pancréatiques (TE) est double : il s’agit d’obtenir un contrôle tumoral et un contrôle des sécrétions hormonales. E...
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Chapter
Tumeurs endocrines gastro-entéro-pancréatiques (TE GEP). Classifications, présentations cliniques, marqueurs biologiques
Ce chapitre fait le point sur les classifications, les modalités du diagnostic clinique, le bilan biologique des tumeurs endocrines gastro-entéro-pancréatiques (TE GEP) non à petites cellules (1–5). Nous utili...
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Article
Le cancer de la surrénale. Comment optimiser la prise en charge d’un cancer rare? UPC Inca, COMETE
Adrenal cancers (adrenal cortical carcinoma, malignant pheochromocytoma and paraganglioma) are rare tumours that may occur as a familial disease. Medical treatments did not show any efficiency in the managemen...
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Article
Motesanib difosfato nel cancro tiroideo differenziato progressivo
PREMESSE: L’espressione del vascular endothelial growth factor (VEGF) è tipica dei carcinomi tiroidei differenziati ed è associata ad un comportamento aggressivo e ad una evoluzione sfavorevole. Il motesanib difo...
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Chapter
Localisation gastro-intestinale
Les tumeurs neuro-endocrines (TE) sont définies par l’expression de protéines de structure des granules et vésicules de sécrétion: la chromogranine A et la synaptophysine. Cette définition commun...
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Article
Endocrine pancreatic tumours: which are the most useful MRI sequences?
To determine magnetic resonance imaging (MRI) signal and enhancement characteristics of endocrine pancreatic tumours (ETPs) and which MR sequences show them most consistently.
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Article
La positività della 18FDG-PET/TC a carico della ghiandola surrenalica controlaterale in pazienti surrenectomizzati per carcinoma surrenalico non è marker di malignità
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Article
Therapeutic Management of Advanced Adrenocortical Carcinoma: What Do We Know in 2011?
The prognosis of advanced adrenocortical carcinoma (ACC) is dismal but heterogeneous. In 2011, mitotane is the only drug approved in Europe and US for the treatment of advanced ACC. Mitotane exerts both antise...
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Article
Patologia surrenalica nella MEN-1. Analisi di 715 casi dal database “Groupe d’étude des tumeurs endocrines”
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Article
Efficacia di everolimus in pazienti con insulinoma metastatico ed ipoglicemia refrattaria
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Article
Caractérisation des tumeurs neuroendocrines digestives ou thoraciques
Once the diagnosis of a neuroendocrine tumour has been made, characterisation is an essential step before therapy. It comes before the decision regarding treatment is made. This requires a multidisciplinary te...