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  1. Article

    Open Access

    Pancreatic adenocarcinoma third line systemic treatments: a retrospective cohort study

    Chemotherapy for metastatic pancreatic adenocarcinoma (PDAC) primarily relies on FOLFIRINOX (LV5FU- irinotecan – Oxaliplatine) and Gemcitabine – Nab-Paclitaxel in the first-line setting. However, second-lines ...

    A. Gueiderikh, A. Tarabay, M. Abdelouahab, C. Smolenschi, M. L. Tanguy in BMC Cancer (2024)

  2. No Access

    Article

    The Frequency of Germline BRCA and Non-BRCA HR-Gene-Variants in a Cohort of Pancreatic Cancer Patients

    Germline DNA alterations affecting homologous recombination pathway genes have been associated with pancreatic cancer (PC) risk. BRCA2 is the most studied gene and affects the management of PC patients and the...

    M. Baz, V. Gondran-Teiller, B. Bressac, O. Cabaret in Digestive Diseases and Sciences (2023)

  3. No Access

    Article

    Is intra-arterial hepatic chemotherapy painful?

    Liver metastases are mainly supplied by the hepatic artery, allowing the administration of intra-arterial hepatic chemotherapy (IAHC) while preserving normal parenchyma. The progression-free survival and respo...

    F. Kerbage, T. Grinda, C. Smolenschi, V. Boige, D. Malka in Supportive Care in Cancer (2020)

  4. Article

    Open Access

    Design of fiber-integrated tunable thermo-optic C-band filter based on coated silicon slab

    Optical filters are required to have narrow band-pass filtering in the spectral C-band for applications such as signal tracking, sub-band filtering or noise suppression. These requirements lead to a variety of...

    H. Pinhas, D. Malka, Y. Danan, M. Sinvani in Journal of the European Optical Society-Ra… (2017)

  5. No Access

    Article

    Hommage à Franck Bonnetain

    I. Krakowski, F. Joly, C. Louvet, D. Malka, J. -F. Seitz in Oncologie (2017)

  6. No Access

    Article

    Chirurgie à visée curative des métastases péritonéales

    L’exérèse complète des métastases péritonéales (MP), suivie de chimiohyperthermie intrapéritonéale (CHIP, dont l’impact thérapeutique précis n’est pas encore connu), permet d’obtenir de nombreuses guérisons ch...

    D. Elias, D. Goéré, C. Honoré, D. Malka, V. Boige, P. Burtin, M. Ducreux in Oncologie (2014)

  7. No Access

    Article

    Chimiothérapie des métastases d’origine colorectale jamais résécables : stratégie multiligne, thérapies ciblées

    Le développement d’anticancéreux plus actifs (oxaliplatine, irinotécan) associés aux thérapies ciblées ainsi que les avancées de la chirurgie ont allongé la survie des patients atteints de cancer colorectal mé...

    V. Boige, D. Malka, C. Ferté, A. Hollebecque, P. Burtin, M. Ducreux in Oncologie (2014)

  8. Article

    Open Access

    Small bowel adenocarcinoma phenoty**, a clinicobiological prognostic study

    Small bowel adenocarcinoma (SBA) is a rare tumour with a poor prognosis. Molecular biology data on SBA carcinogenesis are lacking.

    T Aparicio, M Svrcek, A Zaanan, E Beohou, A Laforest in British Journal of Cancer (2013)

  9. No Access

    Article

    Caractérisation des tumeurs neuroendocrines digestives ou thoraciques

    Once the diagnosis of a neuroendocrine tumour has been made, characterisation is an essential step before therapy. It comes before the decision regarding treatment is made. This requires a multidisciplinary te...

    E. Baudin, J. -Y. Scoazec, C. Caramella, S. Leboulleux, O. Caron, D. Deandreis in Oncologie (2013)

  10. Article

    Open Access

    Tumour-infiltrating CD68+ and CD57+ cells predict patient outcome in stage II–III colorectal cancer

    The aim of our study was to evaluate the prognostic role of immunological microenvironnement in stage II–III CRC patients.

    N Chaput, M Svrcek, A Aupérin, C Locher, F Drusch, D Malka in British Journal of Cancer (2013)

  11. No Access

    Article

    Intra-Arterial Hepatic Chemotherapy: A Comparison of Percutaneous Versus Surgical Implantation of Port-Catheters

    To compare retrospectively the safety and efficacy of percutaneous and surgical implantations of port-catheters for intra-arterial hepatic chemotherapy (IAHC).

    F. Deschamps, D. Elias, D. Goere, D. Malka in CardioVascular and Interventional Radiology (2011)

  12. No Access

    Article

    Chimiothérapie systémique des cancers avancés des voies biliaires: actualités et perspectives

    Biliary tract cancers, with fewer than 2,000 new cases per year in France, must be regarded as orphan tumors. There is currently no evidence of the benefit of neoadjuvant or adjuvant chemotherapy and/or radiot...

    D. Malka, V. Boige, M. Ducreux in Oncologie (2010)

  13. No Access

    Article

    Lymph road map** obtained via blue sentinel node detection to avoid middle colic artery resection for highly selected colon cancer cases: proof of a concept?

    In theory, perioperative detection of lymph nodes with the injection of isosulfan blue dye should provide lymph road map** (LRM) able to direct the resection. However, there is no supporting evidence for thi...

    R. Lo Dico, P. Lasser, D. Goérè, D. Malka, V. Boige in Techniques in Coloproctology (2010)

  14. No Access

    Chapter

    Le traitement médical des cancers colorectaux métastatiques en 2009: quels traitements pour quels patients?

  15. Connaître les autorisations de mise sur le marché (AMM) des différents agents pharmacologiques;

  16. Quelles stratégies pour q...

  17. M. Ducreux, V. Boige, D. Malka, P. Burtin in Post’U FMC-HGE (2009)

  18. No Access

    Article

    Nouveautés dans la chimiothérapie du cancer colorectal métastasé

    La chimiothérapie des cancers colorectaux a été profondément modifiée ces dernières années. Alors même que la place respective de l’irinotécan et de l’oxaliplatine n’était pas complètement définie, les thérapi...

    M. Ducreux, V. Boige, N. Bouarioua, B. Leconte, H. Frikha, T. Boisserie in Oncologie (2008)

  19. No Access

    Chapter

    Tumeurs endocrines gastro-entéro-pancréatiques (TE GEP): facteurs pronostiques

    Ce chapitre fait le point sur les facteurs pronostiques des tumeurs endocrines gastro-entéro-pancréatiques (TE GEP) non à petites cellules (1, 2). Nous utiliserons le terme de « tumeur endocrine », pour définir d...

    É. Baudin, D. Malka, J. Guigay, M. Ducreux in Tumeurs endocrines thoraciques et digestives (2008)

  20. No Access

    Chapter

    Cancer du pancréas exocrine

    D. Malka, J. Desramé in Les cancers digestifs (2006)

  21. No Access

    Article

    Application clinique de la TEP dans la prise en charge du cancer colorectal

    La tomographie par émission de positons ou TEP est le premier examen d’imagerie fonctionnelle disponible en cancérologie. Dans le domaine du cancer colorectal, la TEP a très rapidement occupé une place de choi...

    M. Ducreux, V. Boige, S. Leboulleux, D. Malka, C. Dromain, J. Lumbroso in Oncologie (2005)

  22. No Access

    Article

    Establishment of regional differences in brush border enzymatic activities during the development of fetal mouse small intestine

    In order to study the establishment of regional differences in brush border enzymic activities during the development of fetal mouse small intestine we have followed (1) the differentiation of microvilli by mo...

    Dr. R. Calvert, D. Malka, D. Ménard in Cell and Tissue Research (1981)

  23. No Access

    Article

    Effect of clofibrate on the small intestine of fetal mice

    Pregnant Swiss ICR mice were injected with clofibrate at different dosages and time intervals, and embryos were removed either at 17 or 18 days of gestation. In embryos sacrificed at 17 days the level of intes...

    R. Calvert, D. Malka, D. Ménard in Histochemistry (1979)

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