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Article
Open AccessEvaluating newly approved drugs in combination regimens for multidrug-resistant tuberculosis with fluoroquinolone resistance (endTB-Q): study protocol for a multi-country randomized controlled trial
Treatment for fluoroquinolone-resistant multidrug-resistant/rifampicin-resistant tuberculosis (pre-XDR TB) often lasts longer than treatment for less resistant strains, yields worse efficacy results, and cause...
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Article
Open AccessMesoscopic Klein-Schwinger effect in graphene
Strong electric field annihilation by particle–antiparticle pair creation, also known as the Schwinger effect, is a non-perturbative prediction of quantum electrodynamics. Its experimental demonstration remain...
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Article
Open AccessEvaluating newly approved drugs for multidrug-resistant tuberculosis (endTB): study protocol for an adaptive, multi-country randomized controlled trial
Treatment of multidrug- and rifampin-resistant tuberculosis (MDR/RR-TB) is expensive, labour-intensive, and associated with substantial adverse events and poor outcomes. While most MDR/RR-TB patients do not re...
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Article
Locally unresectable differentiated thyroid cancer: outcomes and perspectives
Differentiated thyroid cancer (DTC) patients with an unresectable primary tumor cannot benefit from curative surgery, and radioiodine treatment for locoregional and distant disease is not possible with the thy...
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Article
Histologically Proven Bronchial Neuroendocrine Tumors in MEN1: A GTE 51-Case Cohort Study
To evaluate the natural history of MEN1-related bronchial endocrine tumors (br-NETs) and to determine their histological characteristics, survival and causes of death.
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Article
Therapeutic Strategies for Advanced Pancreatic Neuroendocrine Tumors with Segmental Portal Hypertension
Pancreatic neuroendocrine tumors (PNET) locally advanced may lead to significant local symptoms especially segmental portal hypertension (SPH) with risk of bleeding. The aim of our study was to evaluate the ro...
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Article
Screening in asymptomatic SDHx mutation carriers: added value of 18F-FDG PET/CT at initial diagnosis and 1-year follow-up
Specific recommendations on screening modalities for paraganglioma (PGL) and phaeochromocytoma (PCC) in asymptomatic SDHx mutation carriers (relatives) are still lacking. We evaluated the added value of 18F-FDG P...
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Article
Thermal ablation techniques: a curative treatment of bone metastases in selected patients?
Thermal ablation techniques (radiofrequency-ablation/cryotherapy) can be indicated with a curative intent. The success rate and prognostic factors for complete treatment were analysed.
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Article
Caractérisation des tumeurs neuroendocrines digestives ou thoraciques
Once the diagnosis of a neuroendocrine tumour has been made, characterisation is an essential step before therapy. It comes before the decision regarding treatment is made. This requires a multidisciplinary te...
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Article
Efficacia di everolimus in pazienti con insulinoma metastatico ed ipoglicemia refrattaria
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Article
Patologia surrenalica nella MEN-1. Analisi di 715 casi dal database “Groupe d’étude des tumeurs endocrines”
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Article
Therapeutic Management of Advanced Adrenocortical Carcinoma: What Do We Know in 2011?
The prognosis of advanced adrenocortical carcinoma (ACC) is dismal but heterogeneous. In 2011, mitotane is the only drug approved in Europe and US for the treatment of advanced ACC. Mitotane exerts both antise...
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Article
La positività della 18FDG-PET/TC a carico della ghiandola surrenalica controlaterale in pazienti surrenectomizzati per carcinoma surrenalico non è marker di malignità
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Article
Endocrine pancreatic tumours: which are the most useful MRI sequences?
To determine magnetic resonance imaging (MRI) signal and enhancement characteristics of endocrine pancreatic tumours (ETPs) and which MR sequences show them most consistently.
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Chapter
Localisation gastro-intestinale
Les tumeurs neuro-endocrines (TE) sont définies par l’expression de protéines de structure des granules et vésicules de sécrétion: la chromogranine A et la synaptophysine. Cette définition commun...
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Article
Motesanib difosfato nel cancro tiroideo differenziato progressivo
PREMESSE: L’espressione del vascular endothelial growth factor (VEGF) è tipica dei carcinomi tiroidei differenziati ed è associata ad un comportamento aggressivo e ad una evoluzione sfavorevole. Il motesanib difo...
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Article
Le cancer de la surrénale. Comment optimiser la prise en charge d’un cancer rare? UPC Inca, COMETE
Adrenal cancers (adrenal cortical carcinoma, malignant pheochromocytoma and paraganglioma) are rare tumours that may occur as a familial disease. Medical treatments did not show any efficiency in the managemen...
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Chapter
Tumeurs endocrines gastro-entéro-pancréatiques (TE GEP): facteurs pronostiques
Ce chapitre fait le point sur les facteurs pronostiques des tumeurs endocrines gastro-entéro-pancréatiques (TE GEP) non à petites cellules (1, 2). Nous utiliserons le terme de « tumeur endocrine », pour définir d...
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Chapter
Chimiothérapie des tumeurs endocrines
Le rôle des traitements médicaux dans la prise en charge des tumeurs endocrines digestives et pancréatiques (TE) est double : il s’agit d’obtenir un contrôle tumoral et un contrôle des sécrétions hormonales. E...
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Chapter
Tumeurs endocrines gastro-entéro-pancréatiques (TE GEP). Classifications, présentations cliniques, marqueurs biologiques
Ce chapitre fait le point sur les classifications, les modalités du diagnostic clinique, le bilan biologique des tumeurs endocrines gastro-entéro-pancréatiques (TE GEP) non à petites cellules (1–5). Nous utili...