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  1. Article

    Open Access

    Pancreatic adenocarcinoma third line systemic treatments: a retrospective cohort study

    Chemotherapy for metastatic pancreatic adenocarcinoma (PDAC) primarily relies on FOLFIRINOX (LV5FU- irinotecan – Oxaliplatine) and Gemcitabine – Nab-Paclitaxel in the first-line setting. However, second-lines ...

    A. Gueiderikh, A. Tarabay, M. Abdelouahab, C. Smolenschi, M. L. Tanguy in BMC Cancer (2024)

  2. No Access

    Article

    Is intra-arterial hepatic chemotherapy painful?

    Liver metastases are mainly supplied by the hepatic artery, allowing the administration of intra-arterial hepatic chemotherapy (IAHC) while preserving normal parenchyma. The progression-free survival and respo...

    F. Kerbage, T. Grinda, C. Smolenschi, V. Boige, D. Malka in Supportive Care in Cancer (2020)

  3. Article

    Open Access

    A Systematic Review of the Burden of Pancreatic Cancer in Europe: Real-World Impact on Survival, Quality of Life and Costs

    The purpose of this study was to assess the overall burden of pancreatic cancer in Europe, with a focus on survival time in a real-world setting, and the overall healthy life lost to the disease.

    A. Carrato, A. Falcone, M. Ducreux, J. W. Valle in Journal of Gastrointestinal Cancer (2015)

  4. No Access

    Article

    Chirurgie à visée curative des métastases péritonéales

    L’exérèse complète des métastases péritonéales (MP), suivie de chimiohyperthermie intrapéritonéale (CHIP, dont l’impact thérapeutique précis n’est pas encore connu), permet d’obtenir de nombreuses guérisons ch...

    D. Elias, D. Goéré, C. Honoré, D. Malka, V. Boige, P. Burtin, M. Ducreux in Oncologie (2014)

  5. No Access

    Article

    Chimiothérapie des métastases d’origine colorectale jamais résécables : stratégie multiligne, thérapies ciblées

    Le développement d’anticancéreux plus actifs (oxaliplatine, irinotécan) associés aux thérapies ciblées ainsi que les avancées de la chirurgie ont allongé la survie des patients atteints de cancer colorectal mé...

    V. Boige, D. Malka, C. Ferté, A. Hollebecque, P. Burtin, M. Ducreux in Oncologie (2014)

  6. No Access

    Article

    Caractérisation des tumeurs neuroendocrines digestives ou thoraciques

    Once the diagnosis of a neuroendocrine tumour has been made, characterisation is an essential step before therapy. It comes before the decision regarding treatment is made. This requires a multidisciplinary te...

    E. Baudin, J. -Y. Scoazec, C. Caramella, S. Leboulleux, O. Caron, D. Deandreis in Oncologie (2013)

  7. Article

    Open Access

    Tumour-infiltrating CD68+ and CD57+ cells predict patient outcome in stage II–III colorectal cancer

    The aim of our study was to evaluate the prognostic role of immunological microenvironnement in stage II–III CRC patients.

    N Chaput, M Svrcek, A Aupérin, C Locher, F Drusch, D Malka in British Journal of Cancer (2013)

  8. No Access

    Article

    Feasibility of cetuximab given with a simplified schedule every 2 weeks in advanced colorectal cancer: a multicenter, retrospective analysis

    Cetuximab was approved using a weekly schedule, alone or in combination with chemotherapy (CT). However, many CT regimens in metastatic colorectal cancer (CRC) are delivered every 2 weeks (q2wks). Preliminary ...

    M. Bouchahda, T. Macarulla, G. LIedo, F. Lévi, M. E. Elez, B. Paule in Medical Oncology (2011)

  9. No Access

    Article

    Intra-Arterial Hepatic Chemotherapy: A Comparison of Percutaneous Versus Surgical Implantation of Port-Catheters

    To compare retrospectively the safety and efficacy of percutaneous and surgical implantations of port-catheters for intra-arterial hepatic chemotherapy (IAHC).

    F. Deschamps, D. Elias, D. Goere, D. Malka in CardioVascular and Interventional Radiology (2011)

  10. No Access

    Article

    Endocrine pancreatic tumours: which are the most useful MRI sequences?

    To determine magnetic resonance imaging (MRI) signal and enhancement characteristics of endocrine pancreatic tumours (ETPs) and which MR sequences show them most consistently.

    C. Caramella, C Dromain, T. De Baere, B. Boulet, M. Schlumberger in European Radiology (2010)

  11. No Access

    Article

    Chimiothérapie systémique des cancers avancés des voies biliaires: actualités et perspectives

    Biliary tract cancers, with fewer than 2,000 new cases per year in France, must be regarded as orphan tumors. There is currently no evidence of the benefit of neoadjuvant or adjuvant chemotherapy and/or radiot...

    D. Malka, V. Boige, M. Ducreux in Oncologie (2010)

  12. No Access

    Chapter

    Localisation gastro-intestinale

    Les tumeurs neuro-endocrines (TE) sont définies par l’expression de protéines de structure des granules et vésicules de sécrétion: la chromogranine A et la synaptophysine. Cette définition commun...

    E. Baudin, D. Elias, C. Dromain, T. De Baere, M. Ducreux in Tumeurs malignes rares (2010)

  13. No Access

    Article

    Immunogenic death of colon cancer cells treated with oxaliplatin

    Both the pre-apoptotic exposure of calreticulin (CRT) and the post-apoptotic release of high-mobility group box 1 protein (HMGB1) are required for immunogenic cell death elicited by anthracyclins. Here, we sho...

    A Tesniere, F Schlemmer, V Boige, O Kepp, I Martins, F Ghiringhelli, L Aymeric in Oncogene (2010)

  14. Article

    Open Access

    Quality-of-life findings from a randomised phase-III study of XELOX vs FOLFOX-6 in metastatic colorectal cancer

    A phase-III trial showed the non-inferiority of oral capecitabine plus oxaliplatin (XELOX) vs 5-fluorouracil/leucovorin plus oxaliplatin (FOLFOX-6) in terms of efficacy in first-line treatment of metastatic color...

    T Conroy, M Hebbar, J Bennouna, M Ducreux, M Ychou, G Llédo in British Journal of Cancer (2010)

  15. No Access

    Chapter

    Le traitement médical des cancers colorectaux métastatiques en 2009: quels traitements pour quels patients?

  16. Connaître les autorisations de mise sur le marché (AMM) des différents agents pharmacologiques;

  17. Quelles stratégies pour q...

  18. M. Ducreux, V. Boige, D. Malka, P. Burtin in Post’U FMC-HGE (2009)

  19. Article

    Open Access

    Phase I trial of oxaliplatin with fluorouracil, folinic acid and concurrent radiotherapy for oesophageal cancer

    This dose escalation study was designed to determine the maximum tolerated dose (MTD) and recommended doses (RDs) of 5-fluorouracil (5FU), folinic acid and oxaliplatin (FOLFOX) with concomitant radiotherapy in...

    T Conroy, F Viret, E François, J F Seitz, V Boige, M Ducreux in British Journal of Cancer (2008)

  20. No Access

    Article

    Le point sur la prise en charge des cancers digestifs

    M. Ychou, M. Ducreux in Oncologie (2008)

  21. No Access

    Article

    Nouveautés dans la chimiothérapie du cancer colorectal métastasé

    La chimiothérapie des cancers colorectaux a été profondément modifiée ces dernières années. Alors même que la place respective de l’irinotécan et de l’oxaliplatine n’était pas complètement définie, les thérapi...

    M. Ducreux, V. Boige, N. Bouarioua, B. Leconte, H. Frikha, T. Boisserie in Oncologie (2008)

  22. No Access

    Article

    Traitement systémique du carcinome hépatocellulaire

    Le bénéfice observé avec les traitements systémiques cytotoxiques reste marginal dans le carcinome hépatocellulaire (CHC) non résécable ou métastatique. Avec l’arrivée des thérapies ciblées, nous assistons act...

    L. Costes, M. Ducreux, V. Boige in Oncologie (2008)

  23. No Access

    Chapter

    Tumeurs endocrines gastro-entéro-pancréatiques (TE GEP): facteurs pronostiques

    Ce chapitre fait le point sur les facteurs pronostiques des tumeurs endocrines gastro-entéro-pancréatiques (TE GEP) non à petites cellules (1, 2). Nous utiliserons le terme de « tumeur endocrine », pour définir d...

    É. Baudin, D. Malka, J. Guigay, M. Ducreux in Tumeurs endocrines thoraciques et digestives (2008)

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