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Article
Italian cross-sectional growth charts for height, weight and BMI (2 to 20 yr)
The aim of this study is to extend to pre-school ages the Italian Society for Pediatric Endocrinology and Diabetes (SIEDP)-2002 growth charts for height, weight and body mass index (BMI), to obtain charts (SIE...
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Article
Functional studies of two novel and two rare mutations in the 21-hydroxylase gene
Congenital adrenal hyperplasia (CAH) is most commonly due to 21-hydroxylase deficiency and presents with a wide spectrum of clinical manifestations, from prenatal virilization and salt-wasting in the neonatal ...
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Article
Final height in a patient with Laron syndrome after long-term therapy with rhIGF-I and short-term therapy with LHRH-analogue and oxandrolone during puberty
Objective: To report our experience on long-term treatment with recombinant-human-IGF-I (rhIGF-I) of a female patient with Laron syndrome (mutation G223G in the GH receptor gene), who received short-term treat...
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Article
Italian cross-sectional growth charts for height, weight and BMI (6–20 y)
Objective To trace growth charts for height, weight and body mass index (BMI) that apply to the whole Italian population. Different charts were drawn for central-north and south Italy since children in central-no...
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Article
Low serum inhibin B levels as a marker of testicular damage after treatment for a childhood malignancy
The aim of this study was to evaluate the role of inhibin B and the determination of its concentration to diagnose testicular damage after treatment for a childhood malignancy. Thirty-seven males treated for ...
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Article
Turner's Syndrome: Cardiologic Profile According to the Different Chromosomal Patterns and Long-Term Clinical Follow-Up of 136 Nonpreselected Patients
The preferential association between Turner's syndrome and congenital heart defects (CHD) have been well known since the first description by Morgagni. There are few studies about the different cardiologic pro...
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Article
Abnormal insulin response to glucose following treatment for Wilms' tumor in childhood
To determine whether β-cell function could be impaired by the treatment for Wilms' tumour (WT) in childhood, we investigated the insulin secretion of 44 survivors of WT (22 males) with a median off-treatment ...
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Article
Longitudinal growth and final height in long-term survivors of childhood leukaemia
Survival of children with acute lymphoblastic leukaemia (ALL) has increased considerably in recent years and data on the spontaneous growth and final height of these children are conflicting. Therefore, we ana...
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Article
Indications for a more aggressive disease process in newly diagnosed insulin-dependent diabetic children in Northern than in Southern Europe
Finland and Sweden have the highest incidence of insulin-dependent diabetes in children in the world, about 3–4 times that of countries in the Mediterranean area, with the exception of Sardinia. We have collec...
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Article
HYPODIPSIA-HYPERNATREMIA SYNDROME - A PEDIATRIC CASE REPORT
The cases of chronic hypodipsis and hypernatremia represent a rarity, especially for the pediatric age group, and are mostly reported as “neurogenic” or “essential” hypernatremia. This paper describes a 2 3/12...
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Article
What will be the adult height of coeliac patients?
We studied three groups of patient with coeliac disease: group 1=95 adult patients with gastro-intestinal symptoms diagnosed after reaching adult height, 41 of whom had had symptoms during childhood; group 2=2...
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Article
Effects of sport (football) on growth auxological, anthropometric and hormonal aspects
There are very few data available on the relationship between sporting activities, endocrine levels and changes in anthropometric measurements during growth. In order to study these relationships, we have made...
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Article
Isolated dehydroepiandrosterone sulphate hypersecretion: A case report
The case of a 17-year-old male with isolated hypersecretion of dehydroepiandrosterone sulphate (DHEAS) is described. Cushing syndrome, congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase defi...
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Article
Long term growth hormone (GH)-releasing hormone and biosynthetic GH therapy in GH-deficient children: comparison of therapeutic effectiveness
Twenty-five GH-deficient children were treated with GHRH (1-44), once daily sc for 6–24 months. At the 6th month of therapy, 40% of our patients showed a catch-up growth (responded), while the remaining 60% di...
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Article
116 GROWTH FACTORS IN HUMAN FOETAL PLASMA DURING THE SECOND TRIMESTER OF GESTATION: “IN UTERO” STUDY
The role of growth factors in fetal development is not clear. Fetal blood was obtained from 61 fetuses aged 19-25 weeks during the course of funicolocentesis performed for: suspected thalassaemia, fetal malfor...
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Article
83 VARIABILITY OF ARGININL-DOPA AND SLEEP TEST PERFORMED TWICE IN THE SAME PATIENTS
We performed arginine and sleep tests (blood samples from latter collected every 30′ for 12 hours) twice within two weeks in 21 short patients with mean C.A. 11.15 years (range 7.5 - 15.91 years); 14 males, 7 ...
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Article
69 HORMONAL, AUXOLOGICAL AND ANTHROPOMETRIC ASPECTS IN YOUNG FOOTBALL PLAYERS
Hormonal parameters (SmC, GH, Testosterone (T) and DHAS), lenght and width measures, body composition and biological maturation (bone age, pubic hair, testicular volume) indicators were used to evaluate during...
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Article
136 TREATMENT OF PRECOCIOUS PUBERTY BY INIRANASAL D-SER (TBU)6 LHRHI – 9EA10(BUSERELIN
GnRH analogues afford effective, selective, reversible inhibition of pituitary gonadotropin secretion. We administered Buserelin (300 ug × 6/die) to 18 girls affected by precocious puberty, for 6-24 months (on...
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Article
150 GONADAL HITOLOGY IN TWENTY SUBJECTS WITH MAL PSEUDO – HERNAFRODITISM
Gonadal histology was investigated by means of conventional microscopy in 11 Complete Adrogen insensitivity Syndrome (CAIS), in 5 Incomplete Adrogen Insensitivity Syndrome (IAIS) and in 4 5αreductase deficienc...
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Article
115 EFFECT OF GONADECTOMY ON GROWTH FACTORS IN TESTICULAR FENINIZED CHILDREN
Sm-C increase during puberty or sex hormones treatment. Whether this increase is mediated by GH is still unclear. Children with testicular feminization submitted to gonadectomy provide a good model to assess t...
