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Article
MAGNETIC RESONANCE IMAGING (MRI) IN PATIENTS WITH MULTIPLE PITUITARY HORMONE DEFICIENCIES (MPHD)
The aim of this study was to evaluate with magnetic resonance imaging (MRI) the hypothalamic and pituitary structures in patients with idiopathic isolated growth hormone deficiency (GHD) or multiple pituitary ...
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Article
Long term growth hormone (GH)-releasing hormone and biosynthetic GH therapy in GH-deficient children: comparison of therapeutic effectiveness
Twenty-five GH-deficient children were treated with GHRH (1-44), once daily sc for 6–24 months. At the 6th month of therapy, 40% of our patients showed a catch-up growth (responded), while the remaining 60% di...
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Article
Effect of human chorionic gonadotropin on growth velocity and biological growth parameters in adolescents with thalassaemia major
The effect of long-term human chorionic gonadotropin (HCG) therapy on the linear growth and biological growth parameters was studied in six thalassaemic boys aged 14.5–15.5 years old with hypogonadotropic hypo...
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Article
Effectiveness of growth hormone (GH) therapy in GH-deficient children and non-GH-deficient short children
The growth response during short-term growth hormone (GH) treatment was evaluated in eight prepubertal non-GH-deficient (non-GHD) children and compared with six prepubertal GH-deficient (GHD) patients. Standar...
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Article
INFLUENCE OF BIOSYNTHETIC GROWTH HORMONE (GH) THERAPY ON THE IMMUNE SYSTEM OF GH-DEFICIENT CHILDREN
The ability of GH to influence humoral and cell-mediated immunity was evaluated in 21 GH-deficient children, 1.8-17.7 yr, before and during therapy with biosynthetic GH (Somatonorm)(12U/mq)im injected three ti...