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  1. No Access

    Article

    Immune Features of Tumor Microenvironment: A Genetic Spotlight

    A tumor represents a highly intricate tissue entity, characterized by an exceptionally complex microenvironment that starkly contrasts with the typical physiological surroundings of healthy tissues. Within thi...

    Milad Asadi, Habib Zarredar, Venus Zafari… in Cell Biochemistry and Biophysics (2024)

  2. No Access

    Article

    siRNA-mediated downregulation of BATF3 diminished proliferation and induced apoptosis through downregulating c-Myc expression in chronic myelogenous leukemia cells

    Despite considerable improvement in therapeutic approaches to chronic myeloid leukemia (CML) treatment, this malignancy is considered incurable due to resistance. However, investigating the molecular mechanism...

    Reza Dabbaghipour, Vahid Khaze Shahgoli, Sahar Safaei… in Molecular Biology Reports (2024)

  3. No Access

    Article

    The cross-talk between leptin and circadian rhythm signaling proteins in physiological processes: a systematic review

    Today, modern lifestyles and disrupted sleep patterns cause circadian clock rhythm impairments that are associated with altered leptin levels, which subsequently affect a wide range of physiological processes ...

    Atefeh Ansarin, Aida Malek Mahdavi, Zeinab Javadivala… in Molecular Biology Reports (2023)

  4. No Access

    Article

    MicroRNAs expression in peripheral blood mononuclear cells of patients with multiple sclerosis propose

    MicroRNAs (miRs) are involved in the autoimmune and neurological diseases, including multiple sclerosis (MS), through modulating post-transcriptional gene regulation. Accumulating evidence indicates that miR-1...

    Mahsa Abolghasemi, Sepide Ali Ashrafi, Milad Asadi… in Molecular Biology Reports (2023)

  5. Article

    Open Access

    The production of the first functional antibody mimetic in higher plants: the chloroplast makes the DARPin G3 for HER2 imaging in oncology

    Designed mimetic molecules are attractive tools in biopharmaceuticals and synthetic biology. They require mass and functional production for the assessment of upcoming challenges in the near future. The DARPin...

    Maryam Ehsasatvatan, Bahram Baghban Kohnehrouz, Ashraf Gholizadeh… in Biological Research (2022)

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  6. Article

    Open Access

    Exosome application in treatment and diagnosis of B-cell disorders: leukemias, multiple sclerosis, and arthritis rheumatoid

    Exosomes, known as a type of extracellular vesicles (EVs), are lipid particles comprising heterogeneous contents such as nucleic acids, proteins, and DNA. These bi-layered particles are naturally released into...

    Mohsen Karami Fath, Jalil Azami, Niloofar Jaafari… in Cellular & Molecular Biology Letters (2022)

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  7. No Access

    Article

    Investigation of molecular cryopreservation, fertility potential and microRNA-mediated apoptosis in Oligoasthenoteratozoospermia men

    Investigation of the cryo-injury mechanism can provide novel insight into cryopreservation. The objective of this study is to assess the effect of cryopreservation on fertility potential, motility, oxidative s...

    Maryam Ezzati, Dariush Shanehbandi, Behzad Bahramzadeh… in Cell and Tissue Banking (2021)

  8. No Access

    Article

    Influence of cryopreservation on structure and function of mammalian spermatozoa: an overview

    Cryopreservation is a useful approach to preserve male fertility for assisted reproduction technique and other evaluations. In spite of extensive development in the cryopreservation field, there are biological...

    Maryam Ezzati, Dariush Shanehbandi, Kobra Hamdi, Sara Rahbar… in Cell and Tissue Banking (2020)