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  1. Article

    Open Access

    Exploring the dynamic interplay between exosomes and the immune tumor microenvironment: implications for breast cancer progression and therapeutic strategies

    Breast cancer continues to pose a substantial worldwide health concern, demanding a thorough comprehension of the complex interaction between cancerous cells and the immune system. Recent studies have shown th...

    Sahar Safaei, Manouchehr Fadaee, Omid Rahbar Farzam… in Breast Cancer Research (2024)

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  2. No Access

    Article

    siRNA-mediated downregulation of BATF3 diminished proliferation and induced apoptosis through downregulating c-Myc expression in chronic myelogenous leukemia cells

    Despite considerable improvement in therapeutic approaches to chronic myeloid leukemia (CML) treatment, this malignancy is considered incurable due to resistance. However, investigating the molecular mechanism...

    Reza Dabbaghipour, Vahid Khaze Shahgoli, Sahar Safaei… in Molecular Biology Reports (2024)

  3. No Access

    Article

    NRF2 Suppression Enhances the Susceptibility of Pancreatic Cancer Cells, Miapaca-2 to Paclitaxel

    Pancreatic cancer is one of the most deadly diseases, with a very high metastasis and low survival rate. High levels of NRF2 have been detected in numerous malignancies, including head, neck, lung, and colon c...

    Negin Riazi-Tabrizi, Mohammad Khalaj-Kondori, Sahar Safaei… in Molecular Biotechnology (2023)

  4. No Access

    Article

    CD133 suppression increases the sensitivity of prostate cancer cells to paclitaxel

    One of the major barriers in cancer therapy is the resistance to conventional therapies and cancer stem cells (CSCs) are among the main causes of this problem. CD133 as a CSC marker displays stem cell-like pro...

    Marjan Aghajani, Ahad Mokhtarzadeh, Leili Aghebati-Maleki… in Molecular Biology Reports (2020)