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  1. Article

    Open Access

    Immunoinformatics design of a structural proteins driven multi-epitope candidate vaccine against different SARS-CoV-2 variants based on fynomer

    The ideal vaccines for combating diseases that may emerge in the future require more than simply inactivating a few pathogenic strains. This study aims to provide a peptide-based multi-epitope vaccine effectiv...

    Javad Sarvmeili, Bahram Baghban Kohnehrouz, Ashraf Gholizadeh in Scientific Reports (2024)

  2. Article

    Open Access

    The production of the first functional antibody mimetic in higher plants: the chloroplast makes the DARPin G3 for HER2 imaging in oncology

    Designed mimetic molecules are attractive tools in biopharmaceuticals and synthetic biology. They require mass and functional production for the assessment of upcoming challenges in the near future. The DARPin...

    Maryam Ehsasatvatan, Bahram Baghban Kohnehrouz, Ashraf Gholizadeh in Biological Research (2022)

  3. No Access

    Article

    Pectin methylesterase activity of plant DUF538 protein superfamily

    DUF538 (domain of unknown function 538) proteins are known as a group of putative hypothetical proteins in a wide range of plant species. They have been identified from some plants challenged with various envi...

    Ashraf Gholizadeh in Physiology and Molecular Biology of Plants (2020)

  4. No Access

    Article

    Purification of a ribosome-inactivating protein with antioxidation and root developer potencies from Celosia plumosa

    Considering Celosia plumosa as a potent antiviral plant, the attempt was made to determine, purify and characterize its proteinaceous antiviral elements against tobacco mosaic virus hypersensitive response on Nic...

    Ashraf Gholizadeh in Physiology and Molecular Biology of Plants (2019)

  5. No Access

    Article

    Chlorophyll Binding Ability of Non-chloroplastic DUF538 Protein Superfamily in Plants

    The type-1 water soluble chlorophyll binding proteins (WSCP1) have been generally known as chlorophyll extractors and transporters from the thylakoid membrane to the chloroplast envelope, where the membrane bo...

    Ashraf Gholizadeh in Proceedings of the National Academy of Sci… (2018)

  6. No Access

    Article

    DUF538 protein superfamily is predicted to be chlorophyll hydrolyzing enzymes in plants

    The possible hydrolytic activity towards chlorophyll molecules was predicted for DUF538 protein superfamily in plants. It was examined by using computational as well as experimental tools including in vitro chlor...

    Ashraf Gholizadeh in Physiology and Molecular Biology of Plants (2016)

  7. No Access

    Article

    DUF538 Protein Super Family is Predicted to be the Potential Homologue of Bactericidal/Permeability-Increasing Protein in Plant System

    DUF538 protein super family includes a number of plant proteins that their role is not yet clear. These proteins have been frequently reported to be expressed in plants under various stressful stimuli such as ...

    Ashraf Gholizadeh, Samira Baghban Kohnehrouz in The Protein Journal (2013)

  8. No Access

    Article

    Molecular analysis of maize cystatin expression as fusion product in Escherichia coli

    Nowadays, plant cysteine proteinase inhibitors “namely phytocystatins” have attracted researchers towards the identification of their molecular structures and novel physiological functions. Their important rol...

    Ashraf Gholizadeh in Physiology and Molecular Biology of Plants (2012)

  9. No Access

    Article

    Heterologous Expression of Stress-Responsive DUF538 Domain Containing Protein and its Morpho-Biochemical Consequences

    As a usual response, plants induce/activate various proteins which are thought to be involved in defense mechanisms against the biotic and abiotic stresses they may be confronted with. The novel DUF538 domain ...

    Ashraf Gholizadeh in The Protein Journal (2011)

  10. No Access

    Article

    Antioxidant Activity of Antiviral Proteins from Celosia cristata

    The antioxidant activity test of Celosia cristata antiviral proteins (CCP-25 and CCP-27) using ferric reducing antioxidant power (FRAP) assay in vitro indicated that these proteins are strong antioxidants. The in...

    Ashraf Gholizadeh, Manoj Kumar in Journal of Plant Biochemistry and Biotechn… (2004)