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  1. No Access

    Article

    DNA methylation aberrancies delineate clinically distinct subsets of colorectal cancer and provide novel targets for epigenetic therapies

    Colorectal cancer (CRC) is a worldwide health concern with respect to both incidence and mortality, and as a result, CRC tumorigenesis, progression and metastasis have been heavily studied, especially with res...

    D J Weisenberger, G Liang, H-J Lenz in Oncogene (2018)

  2. No Access

    Article

    DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status

    In an initial epigenetic characterization of diffuse large B-cell lymphoma (DLBCL), we evaluated the DNA methylation levels of over 500 CpG islands. Twelve CpG islands (AR, CDKN1C, DLC1, DRD2, GATA4, GDNF, GRIN2B

    B L Pike, T C Greiner, X Wang, D D Weisenburger, Y-H Hsu, G Renaud… in Leukemia (2008)

  3. No Access

    Article

    Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors

    How hypermethylation and hypomethylation of different parts of the genome in cancer are related to each other and to DNA methyltransferase (DNMT) gene expression is ill defined. We used ovarian epithelial tumo...

    M Ehrlich, C B Woods, M C Yu, L Dubeau, F Yang, M Campan, D J Weisenberger… in Oncogene (2006)

  4. No Access

    Chapter

    DNA Methylation Profiles of Female Steroid Hormone-Driven Human Malignancies

    Tumor DNA contains valuable clues about the origin and pathogenesis of human cancers. Alterations in DNA methylation can lead to silencing of genes associated with distinct tumorigenic pathways. These pathway-...

    M. Campan, D. J. Weisenberger, P. W. Laird in DNA Methylation: Development, Genetic Dise… (2006)