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  1. No Access

    Article

    Combined copy number and mutation analysis identifies oncogenic pathways associated with transformation of follicular lymphoma

    Follicular lymphoma (FL) is typically an indolent disease, but 30–40% of FL cases transform into an aggressive lymphoma (tFL) with a poor prognosis. To identify the genetic changes that drive this transformati...

    A Bouska, W Zhang, Q Gong, J Iqbal, A Scuto, J Vose, M Ludvigsen, K Fu… in Leukemia (2017)

  2. No Access

    Article

    Recurrent activating mutations of CD28 in peripheral T-cell lymphomas

    Peripheral T-cell lymphomas (PTCLs) comprise a heterogeneous group of mature T-cell neoplasms with a poor prognosis. Recently, mutations in TET2 and other epigenetic modifiers as well as RHOA have been identif...

    J Rohr, S Guo, J Huo, A Bouska, C Lachel, Y Li, P D Simone, W Zhang, Q Gong… in Leukemia (2016)

  3. Article

    Erratum: Natural killer cell lymphoma shares strikingly similar molecular features with a group of non-hepatosplenic γδ T-cell lymphoma and is highly sensitive to a novel aurora kinase A inhibitor in vitro

    Correction to: Leukemia (2011) 25, 348–358 doi:10.1038/leu.2010.255 Since the publication of this paper, the authors have noticed an error in Supplementary Table 1. The ethnicity of the Jurkat cell line was in...

    J Iqbal, D D Weisenburger, A Chowdhury, M Y Tsai, G Srivastava, T C Greiner… in Leukemia (2011)

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    Article

    Natural killer cell lymphoma shares strikingly similar molecular features with a group of non-hepatosplenic γδ T-cell lymphoma and is highly sensitive to a novel aurora kinase A inhibitor in vitro

    Natural killer (NK) cell lymphomas/leukemias are rare neoplasms with an aggressive clinical behavior. The majority of the cases belong to extranodal NK/T-cell lymphoma, nasal type (ENKTL) in the current WHO cl...

    J Iqbal, D D Weisenburger, A Chowdhury, M Y Tsai, G Srivastava, T C Greiner… in Leukemia (2011)

  5. No Access

    Article

    DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status

    In an initial epigenetic characterization of diffuse large B-cell lymphoma (DLBCL), we evaluated the DNA methylation levels of over 500 CpG islands. Twelve CpG islands (AR, CDKN1C, DLC1, DRD2, GATA4, GDNF, GRIN2B

    B L Pike, T C Greiner, X Wang, D D Weisenburger, Y-H Hsu, G Renaud… in Leukemia (2008)

  6. No Access

    Article

    Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells

    Mdm2, a regulator of the p53 tumor suppressor, is frequently overexpressed in lymphomas, including lymphomas that have inactivated p53. However, the biological consequences of Mdm2 overexpression in lymphocyte...

    P Wang, T Lushnikova, J Odvody, T C Greiner, S N Jones, C M Eischen in Oncogene (2008)

  7. No Access

    Article

    Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma

    Gene expression profiling of diffuse large B-cell lymphoma (DLBCL) has revealed biologically and prognostically distinct subgroups: germinal center B-cell-like (GCB), activated B-cell-like (ABC) and primary me...

    J Iqbal, T C Greiner, K Patel, B J Dave, L Smith, J Ji, G Wright, W G Sanger… in Leukemia (2007)

  8. No Access

    Article

    Decreased Mdm2 expression inhibits tumor development induced by loss of ARF

    The tumor suppressor p14/p19ARF regulates Mdm2, which is known for controlling the p53 tumor suppressor. Here we report that loss of one allele of Mdm2 in cells that lack ARF resulted in a decreased rate of proli...

    P Wang, T C Greiner, T Lushnikova, C M Eischen in Oncogene (2006)