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  1. Article

    Open Access

    The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution

    Microscopy by Achromatic X-rays With Emission of Laminar Light (MAXWELL) is a new X-ray/visible technique with attractive characteristics including isotropic resolution in all directions, large-volume imaging ...

    Yoshiki Kohmura, Shun-Min Yang, Hsiang-Hsin Chen, Hidekazu Takano in Scientific Reports (2022)

  2. Article

    Open Access

    Author Correction: Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Christina Vrahnas, Martha Blank, Toby A. Dite, Liliana Tatarczuch in Nature Communications (2019)

  3. Article

    Open Access

    Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone

    Mineralized bone forms when collagen-containing osteoid accrues mineral crystals. This is initiated rapidly (primary mineralization), and continues slowly (secondary mineralization) until bone is remodeled. Th...

    Christina Vrahnas, Martha Blank, Toby A. Dite, Liliana Tatarczuch in Nature Communications (2019)

  4. No Access

    Article

    FTIR spectroscopy characterization of fatty-acyl-chain conjugates

    FTIR spectroscopy is used to identify poly-l-lysin fatty-acyl-chain (PLL-FAC) conjugates based on structural differences found between FAC species. Twenty-one PLL-FAC models were used, from C8 to C24, and with up...

    Vladimir Bobroff, Cyril Rubio, Valérie Vigier in Analytical and Bioanalytical Chemistry (2016)

  5. Article

    Open Access

    Gold nanoparticles as multimodality imaging agents for brain gliomas

    Nanoparticles can be used for targeted drug delivery, in particular for brain cancer therapy. However, this requires a detailed analysis of nanoparticles from the associated microvasculature to the tumor, not ...

    Sheng-Feng Lai, Bai-Hung Ko, Chia-Chi Chien, Chia-Ju Chang in Journal of Nanobiotechnology (2015)

  6. No Access

    Article

    Fourier-transform-infrared-spectroscopy based spectral-biomarker selection towards optimum diagnostic differentiation of oral leukoplakia and cancer

    In search of specific label-free biomarkers for differentiation of two oral lesions, namely oral leukoplakia (OLK) and oral squamous-cell carcinoma (OSCC), Fourier-transform infrared (FTIR) spectroscopy was pe...

    Satarupa Banerjee, Mousumi Pal in Analytical and Bioanalytical Chemistry (2015)

  7. Article

    Erratum to: The role of asbestos morphology on their cellular toxicity: an in vitro 3D Raman/Rayleigh imaging study

    Seydou Yao, Hsiang-Hsin Chen, Etienne Harte in Analytical and Bioanalytical Chemistry (2013)

  8. No Access

    Article

    FTIR spectro-imaging of collagen scaffold formation during glioma tumor development

    Evidence has recently emerged that solid and diffuse tumors produce a specific extracellular matrix (ECM) for division and diffusion, also develo** a specific interface with microvasculature. This ECM is mai...

    Razia Noreen, Chia-Chi Chien, Hsiang-Hsin Chen in Analytical and Bioanalytical Chemistry (2013)

  9. Article

    Morpho-spectral imaging in the biosciences

    Cyril Petibois, Yeukuang Hwu in Analytical and Bioanalytical Chemistry (2013)

  10. No Access

    Article

    The role of asbestos morphology on their cellular toxicity: an in vitro 3D Raman/Rayleigh imaging study

    Amphiboles caused cohorts of deaths in exposed workers, leading to some of the largest class actions in the industry. Once inhaled, these inorganic fibers are thought to be both chemically and morphologically ...

    Yao Seydou, Hsiang-Hsin Chen, Etienne Harte in Analytical and Bioanalytical Chemistry (2013)

  11. No Access

    Article

    Use of synchrotron-radiation-based FTIR imaging for characterizing changes in cell contents

    FTIR imaging of individual cells is still limited by the low signal-to-noise ratio obtained from analysis of such weakly absorbing organic matter when using a Globar IR source. In this study, we used FTIR imag...

    Seydou Yao, Michel Moenner, Anders Engdahl in Analytical and Bioanalytical Chemistry (2012)

  12. Article

    Morpho-spectral imaging for investigation of disease progression

    Cyril Petibois in Analytical and Bioanalytical Chemistry (2012)

  13. Article

    Open Access

    X-ray imaging of tumor growth in live mice by detecting gold-nanoparticle-loaded cells

    We show that sufficient concentrations of gold nanoparticles produced by an original synthesis method in EMT-6 and CT-26 cancer cells make it possible to detect the presence, necrosis and proliferation of such...

    Chia-Chi Chien, Hsiang-Hsin Chen, Sheng-Feng Lai, Y. Hwu in Scientific Reports (2012)

  14. Article

    Open Access

    Gold nanoparticles as high-resolution X-ray imaging contrast agents for the analysis of tumor-related micro-vasculature

    Angiogenesis is widely investigated in conjunction with cancer development, in particular because of the possibility of early stage detection and of new therapeutic strategies. However, such studies are negati...

    Chia-Chi Chien, Hsiang-Hsin Chen, Sheng-Feng Lai in Journal of Nanobiotechnology (2012)

  15. No Access

    Article

    Orientation of molecular groups of fibers in nonoriented samples determined by polarized ATR-FTIR spectroscopy

    A method based on polarized attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy is proposed for determining the infrared dichroic absorption ratio of a single fiber from a sample dep...

    Karima Belbachir, Sophie Lecomte, Ha-Phuong Ta in Analytical and Bioanalytical Chemistry (2011)

  16. Article

    The emergence of multimodal imaging methods for real-time nanoscopy

    Cyril Petibois in Analytical and Bioanalytical Chemistry (2011)

  17. No Access

    Article

    Functional histology of glioma vasculature by FTIR imaging

    Fourier-transform infrared (FTIR) imaging has been used to investigate brain tumor angiogenesis using a mice solid tumor model and bare-gold (∅ 25 nm) or BaSO4 (∅ 500 nm) nanoparticles (NP) injected into blood va...

    Razia Noreen, Raphael Pineau, Chia-Chi Chien in Analytical and Bioanalytical Chemistry (2011)

  18. No Access

    Article

    Detection of collagens in brain tumors based on FTIR imaging and chemometrics

    Fourier transform infrared (FTIR) imaging has been used as a molecular histopathology tool on brain tissue sections after intracranial implantation and development of glioma tumors. Healthy brain tissue (contr...

    Razia Noreen, Chia-Chi Chien, Maylis Delugin in Analytical and Bioanalytical Chemistry (2011)

  19. Article

    Open Access

    Quantitative analysis of nanoparticle internalization in mammalian cells by high resolution X-ray microscopy

    Quantitative analysis of nanoparticle uptake at the cellular level is critical to nanomedicine procedures. In particular, it is required for a realistic evaluation of their effects. Unfortunately, quantitative...

    Hsiang-Hsin Chen, Chia-Chi Chien, Cyril Petibois in Journal of Nanobiotechnology (2011)

  20. Article

    Imaging techniques with synchrotron radiation

    Cyril Petibois in Analytical and Bioanalytical Chemistry (2010)

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