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Open AccessThe new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution
Microscopy by Achromatic X-rays With Emission of Laminar Light (MAXWELL) is a new X-ray/visible technique with attractive characteristics including isotropic resolution in all directions, large-volume imaging ...
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Open AccessAuthor Correction: Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessIncreased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone
Mineralized bone forms when collagen-containing osteoid accrues mineral crystals. This is initiated rapidly (primary mineralization), and continues slowly (secondary mineralization) until bone is remodeled. Th...
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FTIR spectroscopy characterization of fatty-acyl-chain conjugates
FTIR spectroscopy is used to identify poly-l-lysin fatty-acyl-chain (PLL-FAC) conjugates based on structural differences found between FAC species. Twenty-one PLL-FAC models were used, from C8 to C24, and with up...
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Open AccessGold nanoparticles as multimodality imaging agents for brain gliomas
Nanoparticles can be used for targeted drug delivery, in particular for brain cancer therapy. However, this requires a detailed analysis of nanoparticles from the associated microvasculature to the tumor, not ...
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Fourier-transform-infrared-spectroscopy based spectral-biomarker selection towards optimum diagnostic differentiation of oral leukoplakia and cancer
In search of specific label-free biomarkers for differentiation of two oral lesions, namely oral leukoplakia (OLK) and oral squamous-cell carcinoma (OSCC), Fourier-transform infrared (FTIR) spectroscopy was pe...
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Erratum to: The role of asbestos morphology on their cellular toxicity: an in vitro 3D Raman/Rayleigh imaging study
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FTIR spectro-imaging of collagen scaffold formation during glioma tumor development
Evidence has recently emerged that solid and diffuse tumors produce a specific extracellular matrix (ECM) for division and diffusion, also develo** a specific interface with microvasculature. This ECM is mai...
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Morpho-spectral imaging in the biosciences
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The role of asbestos morphology on their cellular toxicity: an in vitro 3D Raman/Rayleigh imaging study
Amphiboles caused cohorts of deaths in exposed workers, leading to some of the largest class actions in the industry. Once inhaled, these inorganic fibers are thought to be both chemically and morphologically ...
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Use of synchrotron-radiation-based FTIR imaging for characterizing changes in cell contents
FTIR imaging of individual cells is still limited by the low signal-to-noise ratio obtained from analysis of such weakly absorbing organic matter when using a Globar IR source. In this study, we used FTIR imag...
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Morpho-spectral imaging for investigation of disease progression
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Open AccessX-ray imaging of tumor growth in live mice by detecting gold-nanoparticle-loaded cells
We show that sufficient concentrations of gold nanoparticles produced by an original synthesis method in EMT-6 and CT-26 cancer cells make it possible to detect the presence, necrosis and proliferation of such...
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Open AccessGold nanoparticles as high-resolution X-ray imaging contrast agents for the analysis of tumor-related micro-vasculature
Angiogenesis is widely investigated in conjunction with cancer development, in particular because of the possibility of early stage detection and of new therapeutic strategies. However, such studies are negati...
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Orientation of molecular groups of fibers in nonoriented samples determined by polarized ATR-FTIR spectroscopy
A method based on polarized attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy is proposed for determining the infrared dichroic absorption ratio of a single fiber from a sample dep...
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The emergence of multimodal imaging methods for real-time nanoscopy
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Functional histology of glioma vasculature by FTIR imaging
Fourier-transform infrared (FTIR) imaging has been used to investigate brain tumor angiogenesis using a mice solid tumor model and bare-gold (∅ 25 nm) or BaSO4 (∅ 500 nm) nanoparticles (NP) injected into blood va...
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Detection of collagens in brain tumors based on FTIR imaging and chemometrics
Fourier transform infrared (FTIR) imaging has been used as a molecular histopathology tool on brain tissue sections after intracranial implantation and development of glioma tumors. Healthy brain tissue (contr...
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Open AccessQuantitative analysis of nanoparticle internalization in mammalian cells by high resolution X-ray microscopy
Quantitative analysis of nanoparticle uptake at the cellular level is critical to nanomedicine procedures. In particular, it is required for a realistic evaluation of their effects. Unfortunately, quantitative...
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Imaging techniques with synchrotron radiation