Big Data
9th CCF Conference, BigData 2021, Guangzhou, China, January 8–10, 2022, Revised Selected Papers
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Article
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway
Inflammation disrupts bone metabolism and leads to bone damage. C-reactive protein (CRP) is a typical inflammation marker. Although CRP measurement has been conducted for many decades, how osteoblastic differe...
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Article
Pupil localization algorithm based on lightweight convolutional neural network
Pupil localization is one of the most critical and essential requirements for eye gaze estimation and eye movement tracking. Because pupil images contain monotonous and uncomplicated information, the dataset u...
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Book and Conference Proceedings
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Chapter and Conference Paper
SpEC: Sparse Embedding-Based Community Detection in Attributed Graphs
Community detection, also known as graph clustering, is a widely studied task to find the subgraphs (communities) of related nodes in a graph. Existing methods based on non-negative matrix factorization can so...
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Article
Open AccessIsolation and characterization of phosphofungi, and screening of their plant growth-promoting activities
Rhizospheric microorganisms can increase phosphorus availability in the soil. In this regard, the ability of phosphofungi to dissolve insoluble phosphorus compounds is greater than that of phosphate-solubilizi...
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Article
Open AccessThe combination of nano-calcium sulfate/platelet rich plasma gel scaffold with BMP2 gene-modified mesenchymal stem cells promotes bone regeneration in rat critical-sized calvarial defects
Mesenchymal stem cells (MSCs) can be differentiated into an osteoblastic lineage in the presence of growth factors (GFs). Platelet-rich plasma (PRP), which can be easily isolated from whole blood, contains a l...
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Article
Open AccessBifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors
Directly targeting therapeutic suicide gene to a solid tumor is a hopeful approach for cancer gene therapy. Treatment of a solid tumor by an effective vector for a suicide gene remains a challenge. Given the l...
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Article
Open AccessAnterior arthroscopic-assisted fixation of posterior cruciate ligament avulsion fractures
Avulsion fractures of the tibial insertion of the posterior cruciate ligament (PCL) have always been regarded as rare injuries. The tibial attachment of the PCL is located in an area, which is difficult to acc...
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Chapter and Conference Paper
Research on the Intelligent Public Transportation System
Nowadays, most traditional industries are facing great challenges, and so is the traditional bus industry. To design or renew a route in a metropolis cost our government a considerable amount of money, and hum...
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Article
The overexpression of MCPH1 inhibits cell growth through regulating cell cycle-related proteins and activating cytochrome c-caspase 3 signaling in cervical cancer
MCPH1, initially identified as an hTERT repressor, has recently been implicated in mediating DNA damage response and maintaining chromosome integrity. This study is to investigate its potential role in the ons...
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Article
Kernel and graph: Two approaches for nonlinear competitive learning clusterin
Competitive learning has attracted a significant amount of attention in the past decades in the field of data clustering. In this paper, we will present two works done by our group which address the nonlinearl...
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Article
NFBD1/MDC1 is a protein of oncogenic potential in human cervical cancer
A large nuclear protein of 2089 amino acids, NFBD1/MDC1 has recently been implicated in tumorigenesis and tumor growth. In this study, we investigated its expression in cervical cancers and explored its functi...
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Article
AtMYB12 gene: a novel visible marker for wheat transformation
Efficiency of plant transformation is less than optimal for many important species, especially for monocots which are traditionally recalcitrant to transformation, such as wheat. And due to limited number of s...
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Article
Growth inhibition, morphology change, and cell cycle alterations in NFBD1-depleted human esophageal cancer cells
NFBD1/MDC1 is a large nuclear protein mainly participating in DNA damage response, indicating its therapeutic potential as a radio-/chemosensitizer target in cancer field. Esophageal cancer ranks among one of ...
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Article
Histone Deacetylase Inhibitors Attenuate Acute Lung Injury During Cecal Ligation and Puncture-Induced Polymicrobial Sepsis
The histone deacetylase (HDAC) inhibitors have emerged as the useful reagents that epigenetically modulate the expression of various genes. In the present study, the effects of HDAC inhibitors on the expressio...
