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Article
Open AccessThe influence of subpolar marine ice expansion on global climate in the Early Pleistocene
Major climatic-environmental transitions and ecological shifts occurred during the mid-Early Pleistocene, a time when external forcing conditions were relatively stable. To help elucidate their driving mechani...
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Article
MiR-335 inhibits migration of breast cancer cells through targeting oncoprotein c-Met
Metastasis is the leading cause of death in patients with breast cancer and aberrantly expressed microRNAs (miRNAs) are highly associated with this process. A previous study has shown that miR-335 is downregul...
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Article
The overexpression of MCPH1 inhibits cell growth through regulating cell cycle-related proteins and activating cytochrome c-caspase 3 signaling in cervical cancer
MCPH1, initially identified as an hTERT repressor, has recently been implicated in mediating DNA damage response and maintaining chromosome integrity. This study is to investigate its potential role in the ons...